Evidence map›Paper›PMID 28552460›Full record

ArticleGeneral and comparative endocrinology2017

Ghrelin enhances food intake and carbohydrate oxidation in a nitric oxide dependent manner.

Shayan Abtahi, Aaisha Mirza, Erin Howell, Paul J Currie

Abstract read
In one paragraph

Article in General and comparative endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Tackling Atherosclerosis via Selected Nutrition.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shayan AbtahiDepartment of Psychology, Reed College, Portland, OR, USA.
Aaisha MirzaDepartment of Psychology, Reed College, Portland, OR, USA.
Erin HowellDepartment of Psychology, Reed College, Portland, OR, USA.
Paul J CurrieDepartment of Psychology, Reed College, Portland, OR, USA. Electronic address: pcurrie@reed.edu.
Reed College · US

Funding

Role of Ghrelin in the Induction of Anxiogenic BehaviorR03MH070496 · NIMH · BARNARD COLLEGE · PI CURRIE, PAUL J · 2004 to 2004
$66k
NIMH NIH HHS R03 MH070496
6 · The paper itself

Abstract

In the present study we sought to investigate interactions between hypothalamic nitric oxide (NO) and ghrelin signaling on food intake and energy substrate utilization as measured by the respiratory exchange ratio (RER). Guide cannulae were unilaterally implanted in either the arcuate (ArcN) or paraventricular (PVN) nuclei of male Sprague-Dawley rats. Animals were pretreated with subcutaneous (2.5-10mg/kg/ml) or central (0-100pmol) N-nitro-l-Arginine methyl ester (l-NAME) followed by 50pmol of ghrelin administered into either the ArcN or PVN. Both l-NAME and ghrelin were microinjected at the onset of the active cycle and food intake and RER were assessed 2h postinjection. RER was measured as the ratio of the volume of carbon dioxide expelled relative to the volume of oxygen consumed (VCO

Indexed as

AnimalsArcuate Nucleus of HypothalamusCarbohydratesEatingGhrelinInjections, SubcutaneousMaleNG-Nitroarginine Methyl EsterNitric OxideOxidation-ReductionParaventricular Hypothalamic NucleusRats, Sprague-DawleyRespirationCarbohydratesGhrelinNG-Nitroarginine Methyl EsterNitric OxideAppetiteArcuate nucleusHypothalamusl-NAMEMetabolismParaventricular nucleus

Identifiers

PMID28552460
PMCPMC6885356
OpenAlexW2617660642

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.