Evidence map›Paper›PMID 28552360›Full record

ArticleCurrent biology : CB2017

Paleogenomic Evidence for Multi-generational Mixing between Neolithic Farmers and Mesolithic Hunter-Gatherers in the Lower Danube Basin.

Gloria González-Fortes, Eppie R Jones, Emma Lightfoot, Clive Bonsall, Catalin Lazar, Aurora Grandal-d'Anglade, María Dolores Garralda, Labib Drak, Veronika Siska, Angela Simalcsik and 7 more

Abstract read
In one paragraph

Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Estimating human mobility in Holocene Western Eurasia with large-scale ancient genomic data.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Pooled it
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  7. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
  8. Polygenic prediction of human complex traits using ancient DNA.Current opinion in genetics & development · 2025
    Review
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Gloria González-FortesDepartment of Life Sciences and Biotechnology, University of Ferrara, Via L. Borsari 46, Ferrara 44100, Italy; Institute for Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Straße 24-25, 14476 Potsdam OT Golm, Germany. Electronic address: gnzgrm@unife.it.
Eppie R JonesDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. Electronic address: erj35@cam.ac.uk.
Emma LightfootMcDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge CB2 3ER, UK.
Clive BonsallSchool of History, Classics and Archaeology, University of Edinburgh, William Robertson Wing, Old Medical School, Teviot Place, Edinburgh EH8 9AG, UK.
Catalin LazarNational History Museum of Romania, Bucharest 030026, Romania.
Aurora Grandal-d'AngladeInstituto Universitario de Xeoloxía, Universidade da Coruña, A Coruña 15081, Spain.
María Dolores GarraldaDepartment of Zoology and Physical Anthropology, Complutense University of Madrid, Madrid 28040, Spain.
Labib DrakDepartment of Zoology and Physical Anthropology, Complutense University of Madrid, Madrid 28040, Spain.
Veronika SiskaDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK.
Angela Simalcsik"Olga Necrasov" Centre for Anthropological Research of the Romanian Academy, Iaşi Branch, Theodor Codrescu Strada 2, 700481 Iaşi, Romania.
Adina Boroneanţ"Vasile Pârvan" Institute of Archaeology, Romanian Academy, Henri Coandă Strada 11, Bucharest 010667, Romania.
Juan Ramón Vidal RomaníInstituto Universitario de Xeoloxía, Universidade da Coruña, A Coruña 15081, Spain.
Marcos Vaqueiro RodríguezInstituto Universitario de Xeoloxía, Universidade da Coruña, A Coruña 15081, Spain.
Pablo AriasInternational Institute of Prehistorical Research, University of Cantabria-Government of Cantabria-Bank of Santander, Santander 39005, Spain.
Ron PinhasiSchool of Archaeology and Earth Institute, Belfield, University College Dublin, Dublin 4, Ireland; Department of Anthropology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: ron.pinhasi@ucd.ie.
Andrea ManicaDepartment of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. Electronic address: am315@cam.ac.uk.
Michael HofreiterInstitute for Biochemistry and Biology, University of Potsdam, Karl-Liebknecht-Straße 24-25, 14476 Potsdam OT Golm, Germany. Electronic address: michi@palaeo.eu.

Funding

European Research Council 263441
6 · The paper itself

Abstract

The transition from hunting and gathering to farming involved profound cultural and technological changes. In Western and Central Europe, these changes occurred rapidly and synchronously after the arrival of early farmers of Anatolian origin [1-3], who largely replaced the local Mesolithic hunter-gatherers [1, 4-6]. Further east, in the Baltic region, the transition was gradual, with little or no genetic input from incoming farmers [7]. Here we use ancient DNA to investigate the relationship between hunter-gatherers and farmers in the Lower Danube basin, a geographically intermediate area that is characterized by a rapid Neolithic transition but also by the presence of archaeological evidence that points to cultural exchange, and thus possible admixture, between hunter-gatherers and farmers. We recovered four human paleogenomes (1.1× to 4.1× coverage) from Romania spanning a time transect between 8.8 thousand years ago (kya) and 5.4 kya and supplemented them with two Mesolithic genomes (1.7× and 5.3×) from Spain to provide further context on the genetic background of Mesolithic Europe. Our results show major Western hunter-gatherer (WHG) ancestry in a Romanian Eneolithic sample with a minor, but sizeable, contribution from Anatolian farmers, suggesting multiple admixture events between hunter-gatherers and farmers. Dietary stable-isotope analysis of this sample suggests a mixed terrestrial/aquatic diet. Our results provide support for complex interactions among hunter-gatherers and farmers in the Danube basin, demonstrating that in some regions, demic and cultural diffusion were not mutually exclusive, but merely the ends of a continuum for the process of Neolithization.

Indexed as

ArchaeologyDietGenome, HumanHuman MigrationCultural EvolutionDNA, AncientFarmersHumansLife StyleRomaniaDNA, Ancientancient DNAEneolithicIron GatesMesolithicNeolithic transitionRomania

Identifiers

PMID28552360
PMCPMC5483232

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.