Evidence map›Paper›PMID 28552314›Full record

ArticleNeuron2017

A Series of Suppressive Signals within the Drosophila Circadian Neural Circuit Generates Sequential Daily Outputs.

Xitong Liang, Timothy E Holy, Paul H Taghert

Abstract read
In one paragraph

Article in Neuron, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Soma CaCurrent biology : CB · 2026
    Article
  2. Review
  3. Article
  4. Circadian Control of Lipid Metabolism.Advances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Journal of biological rhythms · 2025
    Article
  7. Article
  8. A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xitong LiangDepartment of Neuroscience, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Timothy E HolyDepartment of Neuroscience, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
Paul H TaghertDepartment of Neuroscience, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA. Electronic address: taghertp@wustl.edu.

Funding

MECHANISMS OF CIRCADIAN CLOCK OUTPUTR01MH067122 · NIMH · WASHINGTON UNIVERSITY · PI TAGHERT, PAUL H · 2003 to 2017
$5.7M
FAST THREE-DIMENSIONAL IMAGING OF NEURONAL ACTIVITY AND PLASTICITYR01NS068409 · NINDS · WASHINGTON UNIVERSITY · PI HOLY, TIMOTHY · 2009 to 2017
$2.7M
MECHANISMS OF CIRCADIAN CLOCK OUTPUTR01NS108393 · NINDS · WASHINGTON UNIVERSITY · PI TAGHERT, PAUL H · 2018 to 2022
$1.6M
WATCHING ACTION POTENTIALS IN INTACT NEURONAL CIRCUITSDP1DA035081 · NIDA · WASHINGTON UNIVERSITY · PI HOLY, TIMOTHY · 2012 to 2013
$1.5M
Expanding Access to Planar Illumination Microscopy in a Neuroimaging CoreR24NS086741 · NINDS · WASHINGTON UNIVERSITY · PI TAGHERT, PAUL H · 2014 to 2017
$814k
NIDA NIH HHS DP1 DA035081NIMH NIH HHS R01 MH067122NINDS NIH HHS R01 NS068409NINDS NIH HHS R01 NS108393NINDS NIH HHS R24 NS086741
6 · The paper itself

Abstract

We studied the Drosophila circadian neural circuit using whole-brain imaging in vivo. Five major groups of pacemaker neurons display synchronized molecular clocks, yet each exhibits a distinct phase of daily Ca

Indexed as

LightAnimalsAnimals, Genetically ModifiedCalciumCircadian RhythmDrosophilaDrosophila ProteinsFeedback, PhysiologicalLocomotionModels, TheoreticalNeuronsNeuropeptidesOptical ImagingCalciumDrosophila ProteinsNeuropeptidespdf protein, Drosophilashort neuropeptide F, Drosophilacalciumcircadian physiologyDrosophilamodulationneuropeptide

Identifiers

PMID28552314
PMCPMC5502710

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.