Evidence map›Paper›PMID 28552170›Full record

ReviewProgress in nuclear magnetic resonance spectroscopy2017

Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.

Darrell D Marshall, Robert Powers

Abstract readReview
In one paragraph

Review in Progress in nuclear magnetic resonance spectroscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Metabolomics: A Viable Approach to Understand the Pathogenesis of Reactive ArthritisEndocrine, metabolic & immune disorders drug targets · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Primary open-angle glaucoma: a perspective from plasma metabolomics.Expert review of molecular diagnostics · 2025
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Polycystic Ovarian Syndrome: A Review of Multi-omics Analyses.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Review
  19. The role of salivary metabolomics in chronic periodontitis: bridging oral and systemic diseases.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Darrell D MarshallDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, United States.
Robert PowersDepartment of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304, United States. Electronic address: rpowers3@unl.edu.

Funding

THE REDOX-MEDIATED REGULATION OF IRON-RESPONSIVE GENE EXPRESSION IN LIVERP20RR017675 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2002 to 2011
$20.4M
Targeting Tumor-Stromal Metabolic Cross-Talk in Pancreatic CancerR01CA163649 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Pankaj Kumar Singh · 2012 to 2026
$5.4M
Redox Biology CenterP30GM103335 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2012 to 2016
$4.3M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015468 · NCRR · UNIVERSITY OF NEBRASKA LINCOLN · PI PAUL, PREM S · 2000 to 2000
$2.0M
Citric acid cycle regulation of exopolysaccharide synthesis in staphylococciR01AI087668 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI SOMERVILLE, GREG ALAN · 2010 to 2013
$1.4M
Essentiality of Mycobacterium tuberculosis D-alanine racemaseR21AI087561 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI CHACON, OFELIA · 2010 to 2011
$393k
NCI NIH HHS R01 CA163649NCRR NIH HHS C06 RR015468NCRR NIH HHS P20 RR017675NIAID NIH HHS R01 AI087668NIAID NIH HHS R21 AI087561NIGMS NIH HHS P30 GM103335
6 · The paper itself

Abstract

Metabolomics is undergoing tremendous growth and is being employed to solve a diversity of biological problems from environmental issues to the identification of biomarkers for human diseases. Nuclear magnetic resonance (NMR) and mass spectrometry (MS) are the analytical tools that are routinely, but separately, used to obtain metabolomics data sets due to their versatility, accessibility, and unique strengths. NMR requires minimal sample handling without the need for chromatography, is easily quantitative, and provides multiple means of metabolite identification, but is limited to detecting the most abundant metabolites (⩾1μM). Conversely, mass spectrometry has the ability to measure metabolites at very low concentrations (femtomolar to attomolar) and has a higher resolution (∼10

Indexed as

MetabolomeHumansIsotope LabelingMagnetic Resonance SpectroscopyMass SpectrometryMetabolomics

Identifiers

PMID28552170
PMCPMC5448308

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.