Evidence map›Paper›PMID 28550648›Full record

ArticleEuropean journal of epidemiology2017

Pregnancy outcome in more than 5000 births to women with viral hepatitis: a population-based cohort study in Sweden.

Knut Stokkeland, Jonas Filip Ludvigsson, Rolf Hultcrantz, Anders Ekbom, Jonas Höijer, Matteo Bottai, Olof Stephansson

Open access · hybridAbstract read
In one paragraph

Article in European journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. [Correlation between hepatitis B virus infection and adverse pregnancy outcomes-a systematic review and meta-analysis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Hepatitis B virus infection, infertility, and assisted reproduction.Journal of Zhejiang University. Science. B · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Prospective cohort study of children exposed to hepatitis C virus through a pregnancy screening program.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Knut StokkelandDepartment of Medicine, Visby Hospital, St Görans Str. 8, 621 84, Visby, Sweden. knut.stokkeland@gotland.se.ORCID 0000-0002-5705-2069
Jonas Filip LudvigssonDepartment of Pediatrics, Örebro University Hospital, Örebro, Sweden.
Rolf HultcrantzDepartment of Medicine, Gastroenterology and Hepatology Unit, Karolinska Institutet, Stockholm, Sweden.
Anders EkbomDepartment of Medicine, Solna, Clinical Epidemiology Unit, Karolinska Hospital and Institutet, Stockholm, Sweden.
Jonas HöijerUnit of Biostatistics, IMM, Karolinska Institutet, Stockholm, Sweden.
Matteo BottaiUnit of Biostatistics, IMM, Karolinska Institutet, Stockholm, Sweden.
Olof StephanssonDepartment of Medicine, Solna, Clinical Epidemiology Unit, Karolinska Hospital and Institutet, Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SEUniversity of Nottingham · GB

Funding

Stockholms Läns Landsting 54224
6 · The paper itself

Abstract

Previous studies have shown inconsistent results with respect to hepatitis B (HBV), hepatitis C (HCV) and pregnancy outcome. The aim of this study was to investigate pregnancy outcome in women with HBV or HCV. In a nationwide cohort of births between 2001 and 2011 we investigated the risks of adverse pregnancy outcomes in 2990 births to women with HBV and 2056 births to women with HCV using data from Swedish healthcare registries. Births to women without HBV (n = 1090 979), and births without HCV (n = 1091 913) served as population controls. Crude and adjusted relative risks (aRR) were calculated using Poisson regression analysis. Women with HCV were more likely to smoke (46.7 vs. 8.0%) and to have alcohol dependence (18.9 vs. 1.3%) compared with population controls. Most women with HBV were born in non-Nordic countries (91.9%). Maternal HCV was associated with a decreased risk of preeclampsia (aRR: 0.39, 95% CI: 0.24-0.64), but an increased risk of preterm birth (aRR: 1.32, 95% CI: 1.08-1.60) and late neonatal death (7-27 days: aRR: 3.79, 95% CI: 1.07-13.39) Preterm birth were also more common in mothers with HBV, aRR: 1.21 (95% CI: 1.02-1.45). Both HBV and HCV are risk factors for preterm birth, while HCV seems to be associated with a decreased risk for preeclampsia. Future studies should corroborate these findings.

Indexed as

AdultCase-Control StudiesFemaleHepatitis BHepatitis CHumansMaternal AgePre-EclampsiaPregnancyPregnancy Complications, InfectiousPregnancy OutcomePremature BirthRegistriesRegression AnalysisRisk FactorsSwedenLate neonatal deathPreeclampsiaPregnancy outcomesPreterm birth

Identifiers

PMID28550648
PMCPMC5570776
OpenAlexW2617446951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.