ArticleScientific reports2017
Multiple viral infections in Agaricus bisporus - Characterisation of 18 unique RNA viruses and 8 ORFans identified by deep sequencing.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 68 citations in OpenAlex.
- The origins and evolution of the RNA virome in land flora.Molecular plant · 2026Article
- Deep sequencing of single Pleurotus ostreatus strain revealed mixed infection of seven RNA viruses.BMC genomics · 2026Article
- Mining viruses in public databases unveils the diversity within the Deltaflexiviridae family.Archives of virology · 2026Article
- Virome of the fungi associated with mushroom dry bubble disease.Virus research · 2026Article
- Mycoviruses confer hypovirulence but enhance antifungal volatile organic compound production in a phytopathogenic fungus.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Identification of a novel mitovirus in grapevine through high-throughput sequencing.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Article
- Discovery of novel RNA viruses through analysis of fungi-associated next-generation sequencing data.BMC genomics · 2024Article
- Deciphering the virome of Chunkung (Cnidium officinale) showing dwarfism-like symptoms via a high-throughput sequencing analysis.Virology journal · 2024Article
- Molecular characterization of a novel mycovirus from binucleate Rhizoctonia AG-A strain A46.Archives of virology · 2024Article
- Meta-transcriptomic analysis reveals the geographical expansion of known sugarbeet-infecting viruses and the occurrence of a novel virus in sugarbeet in the United States.Frontiers in plant science · 2024Article
- Identification and Characterization of a Novel Hypovirus from the Phytopathogenic FungusViruses · 2023Article
- Review
- The RNA virosphere: How big and diverse is it?Environmental microbiology · 2023Article
- Virome analysis of an ectomycorrhizal fungusFrontiers in cellular and infection microbiology · 2023Article
- Multiplex Detection ofCurrent issues in molecular biology · 2022Article
- Natural Populations from theJournal of fungi (Basel, Switzerland) · 2022Article
- Diversity of mycoviruses in edible fungi.Virus genes · 2022Review
- The Mycovirome in a Worldwide Collection of the Brown Rot FungusJournal of fungi (Basel, Switzerland) · 2022Article
- Virome of Three Termite Species from Southern Vietnam.Viruses · 2022Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Thirty unique non-host RNAs were sequenced in the cultivated fungus, Agaricus bisporus, comprising 18 viruses each encoding an RdRp domain with an additional 8 ORFans (non-host RNAs with no similarity to known sequences). Two viruses were multipartite with component RNAs showing correlative abundances and common 3' motifs. The viruses, all positive sense single-stranded, were classified into diverse orders/families. Multiple infections of Agaricus may represent a diverse, dynamic and interactive viral ecosystem with sequence variability ranging over 2 orders of magnitude and evidence of recombination, horizontal gene transfer and variable fragment numbers. Large numbers of viral RNAs were detected in multiple Agaricus samples; up to 24 in samples symptomatic for disease and 8-17 in asymptomatic samples, suggesting adaptive strategies for co-existence. The viral composition of growing cultures was dynamic, with evidence of gains and losses depending on the environment and included new hypothetical viruses when compared with the current transcriptome and EST databases. As the non-cellular transmission of mycoviruses is rare, the founding infections may be ancient, preserved in wild Agaricus populations, which act as reservoirs for subsequent cell-to-cell infection when host populations are expanded massively through fungiculture.
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