Evidence map›Paper›PMID 28550202›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Antigen-Specific T Cell Analysis Reveals That Active Immune Responses to β Cell Antigens Are Focused on a Unique Set of Epitopes.

Junbao Yang, Xiaomin Wen, Hengyu Xu, Nadia Torres-Chinn, Cate Speake, Carla J Greenbaum, Gerald T Nepom, William W Kwok

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulation of macrophage transcriptional dynamics during acute and chronic wound repair.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  4. Review
  5. Review
  6. Breakdown and Repair of Peripheral Immune Tolerance in Type 1 Diabetes.Cold Spring Harbor perspectives in medicine · 2024
    Review
  7. Article
  8. The immunology of type 1 diabetes.Nature reviews. Immunology · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Proinsulin C-peptide is an autoantigen in people with type 1 diabetes.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Junbao YangBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.ORCID 0000-0003-4969-937X
Xiaomin WenBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.ORCID 0000-0002-0472-9021
Hengyu XuBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.
Nadia Torres-ChinnBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.
Cate SpeakeBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.ORCID 0000-0003-1480-4272
Carla J GreenbaumBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.ORCID 0000-0003-4451-9800
Gerald T NepomBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and.ORCID 0000-0002-8063-1464
William W KwokBenaroya Research Institute at Virginia Mason, Seattle, WA 98101; and bkwok@benaroyaresearch.org.
Virginia Mason Medical Center · US

Funding

Phenotypic Analysis of Islet Antigen-specific Effector T Cells in Pre-diabetic SubjectsDP3DK106909 · NIDDK · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI KWOK, WILLIAM W. · 2015 to 2015
$2.2M
NIDDK NIH HHS DP3 DK106909
6 · The paper itself

Abstract

CD38 is an activation marker that is present on recently activated T cells, but absent on resting memory T cells. In this study, we show that CD45RO

Indexed as

AdolescentADP-ribosyl Cyclase 1AdultAutoantigensCation Transport ProteinsCD40 LigandCD4-Positive T-LymphocytesChildDiabetes Mellitus, Type 1Epitope MappingEpitopes, T-LymphocyteFemaleHumansImmunologic MemoryInsulinInsulin-Secreting CellsADP-ribosyl Cyclase 1AutoantigensCation Transport ProteinsCD38 protein, humanCD40 LigandEpitopes, T-LymphocyteInsulinLeukocyte Common AntigensMembrane GlycoproteinspreproinsulinProtein PrecursorsPTPRC protein, humanSLC30A8 protein, humanZinc Transporter 8

Identifiers

PMID28550202
PMCPMC5505653
OpenAlexW2618803347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.