Evidence map›Paper›PMID 28550171›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

β-Adrenergic receptor stimulation inhibits proarrhythmic alternans in postinfarction border zone cardiomyocytes: a computational analysis.

Jakub Tomek, Blanca Rodriguez, Gil Bub, Jordi Heijman

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  4. Review
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  11. Article
  12. BlindedFrontiers in pharmacology · 2019
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jakub TomekLife Sciences Interface Doctoral Training Centre, University of Oxford, Oxford, United Kingdom; jakub.tomek.mff@gmail.com.
Blanca RodriguezDepartment of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, United Kingdom.
Gil BubDepartment of Physiology, McGill University, Montreal, Quebec, Canada; and.
Jordi HeijmanDepartment of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/P001076/1
6 · The paper itself

Abstract

The border zone (BZ) of the viable myocardium adjacent to an infarct undergoes extensive autonomic and electrical remodeling and is prone to repolarization alternans-induced cardiac arrhythmias. BZ remodeling processes may promote or inhibit Ca

Indexed as

Computer SimulationModels, CardiovascularAction PotentialsAdrenergic beta-AgonistsAnimalsArrhythmias, CardiacAutonomic Nervous SystemCalcium SignalingCell CommunicationDogsHeartHumansMyocardial InfarctionMyocytes, CardiacRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumAdrenergic beta-AgonistsRyanodine Receptor Calcium Release Channelalternansborder zonecalciumcomputational modelingmyocardial infarctionβ-adrenergic receptor stimulation

Identifiers

PMID28550171
PMCPMC5582914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.