Evidence map›Paper›PMID 28550108›Full record

ArticleDiabetes2017

Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity.

Jung Dae Kim, Chitoku Toda, Cristina M Ramírez, Carlos Fernández-Hernando, Sabrina Diano

Open access · hybridAbstract read
In one paragraph

Article in Diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  14. Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  15. Article
  16. Remote control of glucose-sensing neurons to analyze glucose metabolism.American journal of physiology. Endocrinology and metabolism · 2018
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jung Dae KimDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Chitoku TodaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT.
Cristina M RamírezDepartment of Comparative Medicine, Yale University School of Medicine, New Haven, CT.
Carlos Fernández-HernandoDepartment of Comparative Medicine, Yale University School of Medicine, New Haven, CT.
Sabrina DianoDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT sabrina.diano@yale.edu.ORCID 0000-0002-7921-2617
Yale University · US

Funding

Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
Mitochondrial Dynamics in VMH Neurons Control Glucose MetabolismR01DK107293 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2015 to 2022
$3.6M
Role of Peroxisome Proliferation in Leptin ResistanceR01DK097566 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2013 to 2020
$3.3M
Central Prolyl Carboxypeptidase (PRCP) in the Regulation of MetabolismR01DK105571 · NIDDK · YALE UNIVERSITY · PI DIANO, SABRINA · 2016 to 2019
$1.5M
NIDDK NIH HHS P30 DK045735NIDDK NIH HHS R01 DK097566NIDDK NIH HHS R01 DK105571NIDDK NIH HHS R01 DK107293
6 · The paper itself

Abstract

The Lin28a/

Indexed as

AnimalsBody WeightDiet, High-FatDown-RegulationEnergy MetabolismGene ExpressionGlucoseGlucose IntoleranceInsulin ResistanceMiceMice, Inbred C57BLObesityProtein Serine-Threonine KinasesProto-Oncogene Proteins c-aktRNA-Binding ProteinsSignal TransductionAkt1 protein, mouseGlucoseLin-28 protein, mouseProtein Serine-Threonine KinasesProto-Oncogene Proteins c-aktRNA-Binding ProteinsTbk1 protein, mouse

Identifiers

PMID28550108
PMCPMC5521863
OpenAlexW2619803124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.