Evidence map›Paper›PMID 28550040›Full record

ArticleBlood2017

KRAS

Tamihiro Kamata, Susan Giblett, Catrin Pritchard

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Early detection of pre-malignant lesions in a KRASDisease models & mechanisms · 2019
    Article
  6. Article
  7. Afatinib restrains K-RAS-driven lung tumorigenesis.Science translational medicine · 2018
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

  • Commented on by
    KRAS2017
5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tamihiro KamataDepartment of Cancer Studies, University of Leicester, Leicester, United Kingdom.
Susan GiblettDepartment of Cancer Studies, University of Leicester, Leicester, United Kingdom.
Catrin PritchardDepartment of Cancer Studies, University of Leicester, Leicester, United Kingdom.
University of Leicester · GB

Funding

Cancer Research UK 13083Cancer Research UK C1362/A13083
6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare histiocytic neoplasm associated with somatic mutations in the genes involved in the RAF/MEK/extracellular signal-regulated kinase (ERK) signaling pathway. Recently, oncogenic mutations in

Indexed as

Histiocytosis, Langerhans-CellLung NeoplasmsMutation, MissenseProto-Oncogene Proteins p21(ras)Amino Acid SubstitutionAnimalsAtorvastatinMiceMice, Mutant StrainsMyeloid CellsAtorvastatinHras protein, mouseProto-Oncogene Proteins p21(ras)

Identifiers

PMID28550040
PMCPMC5562395
OpenAlexW2619996349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.