Evidence map›Paper›PMID 28549463›Full record

ArticleBMC cardiovascular disorders2017

Factors associated with length of stay following trans-catheter aortic valve replacement - a multicenter study.

Yaron Arbel, Nevena Zivkovic, Dhruven Mehta, Sam Radhakrishnan, Stephen E Fremes, Effat Rezaei, Asim N Cheema, Sami Al-Nasser, Ariel Finkelstein, Harindra C Wijeysundera

Abstract readMulticenter Study
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Computed tomography derived anatomical predictors of vascular access complications following transfemoral transcatheter aortic valve implantation: A systematic review.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2024
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  14. Guidelines for Balancing Priorities in Structural Heart Disease During the COVID-19 Pandemic.Cardiovascular revascularization medicine : including molecular interventions · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaron ArbelSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.ORCID 0000-0003-4258-6313
Nevena ZivkovicSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Dhruven MehtaSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Sam RadhakrishnanSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Stephen E FremesSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Effat RezaeiUniversity of Toronto, Toronto, ON, Canada.
Asim N CheemaUniversity of Toronto, Toronto, ON, Canada.
Sami Al-NasserUniversity of Toronto, Toronto, ON, Canada.
Ariel FinkelsteinDepartment of Cardiology, Tel Aviv Medical Center, Tel Aviv, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Harindra C WijeysunderaSchulich Heart Centre, Division of Cardiology and Cardiac surgery, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Harindra.Wijeysundera@sunnybrook.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost patients undergoing Transcatheter aortic valve implantation (TAVR) are elderly with significant co-morbidities and there is limited information available regarding factors that influence length of stay (LOS) post-procedure. The aim of this study was to identify the patient, and procedural factors that affect post-TAVR LOS using a contemporary multinational registry.

methodsWe conducted a retrospective cohort study, with patients recruited from three high volume tertiary institutions. The primary outcome was the LOS post-TAVR procedure. We examined patient and procedural factors in a cause-specific Cox multivariable regression model to elucidate their effect on LOS, accounting for the competing risk of post-procedural death. Hazard ratios (HR) greater than 1 indicate a shorter LOS, while HRs less than 1 indicate a longer LOS.

resultsThe cohort consisted of 809 patients. Patient factors associated with longer LOS were older age, prior atrial fibrillation, and greater patient urgency. Patient factors associated with shorter LOS were lower NYHA class, higher ejection fraction and higher mean aortic valve gradients. Procedural characteristics associated with shorter LOS were conscious sedation (HR = 1.19, 95% CI 1.06-1.35, p = 0.004). Transapical access was associated with prolonged LOS (HR = 0.49, 95% CI 0.41-0.58, p < 0.001).

conclusionThis multicenter study identified potentially modifiable patient and procedural factors associated with a prolonged LOS. Future research is needed to determine if interventions focused on these factors will translate to a shorter LOS.

Indexed as

Length of StayTranscatheter Aortic Valve ReplacementAnesthesia, GeneralAortic ValveAortic Valve StenosisChi-Square DistributionComorbidityHemodynamicsHospital MortalityHospitals, High-VolumeHumansIsraelMultivariate AnalysisOdds RatioOntarioProcedural SedationCompeting risksConscious sedationLength of stayTranscatheter aortic valve replacement

Identifiers

PMID28549463
PMCPMC5446678

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.