Evidence map›Paper›PMID 28549431›Full record

ArticleMalaria journal2017

Insecticide-treated nets provide protection against malaria to children in an area of insecticide resistance in Southern Benin.

John Bradley, Aurore Ogouyèmi-Hounto, Sylvie Cornélie, Jacob Fassinou, Yolande Sissinto Savi de Tove, Adicath Adéola Adéothy, Filémon T Tokponnon, Patrick Makoutode, Alioun Adechoubou, Thibaut Legba and 7 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Evaluation of YaheParasites & vectors · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

John BradleyMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. john.bradley@lshtm.ac.uk.ORCID 0000-0002-9449-4608
Aurore Ogouyèmi-HountoUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Sylvie CornélieInstitut Régional de développement/Centre de Recherche Entomologique de Cotonou, Cotonou, Benin.
Jacob FassinouUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Yolande Sissinto Savi de ToveUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Adicath Adéola AdéothyUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Filémon T TokponnonProgramme National de Lutte contre le paludisme Cotonou, Cotonou, Benin.
Patrick MakoutodeProgramme National de Lutte contre le paludisme Cotonou, Cotonou, Benin.
Alioun AdechoubouProgramme National de Lutte contre le paludisme Cotonou, Cotonou, Benin.
Thibaut LegbaProgramme National de Lutte contre le paludisme Cotonou, Cotonou, Benin.
Telesphore HouansouWorld Health Organization, Geneva, Switzerland.
Dorothée Kinde-GazardUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Martin C AkogbetoInstitut Régional de développement/Centre de Recherche Entomologique de Cotonou, Cotonou, Benin.
Achille MassougbodjiUnité d'Enseignement et de Recherche en Parasitologie-Mycologie de la Faculté des Sciences de la Santé de Cotonou, Cotonou, Benin.
Tessa Bellamy KnoxWorld Health Organization, Geneva, Switzerland.
Martin DonnellyLiverpool School of Tropical Medicine, Liverpool, UK.
Immo KleinschmidtMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Progamme National Contre le Tuberculose · BJWorld Health Organization · CHLiverpool School of Tropical Medicine · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of London · GB

Funding

Medical Research Council MR/K012126/1World Health Organization 001
6 · The paper itself

Abstract

backgroundMalaria control is heavily reliant on insecticides, especially pyrethroids. Resistance of mosquitoes to insecticides may threaten the effectiveness of insecticide-based vector control and lead to a resurgence of malaria in Africa.

methodsIn 21 villages in Southern Benin with high levels of insecticide resistance, the resistance status of local vectors was measured at the same time as the prevalence of malaria infection in resident children.

resultsChildren who used LLINs had lower levels of malaria infection [odds ratio = 0.76 (95% CI 0.59, 0.98, p = 0.033)]. There was no evidence that the effectiveness of nets was different in high and low resistance locations (p = 0.513). There was no association between village level resistance and village level malaria prevalence (p = 0.999).

conclusionsLLINs continue to offer individual protection against malaria infection in an area of high resistance. Insecticide resistance is not a reason to stop efforts to increase coverage of LLINs in Africa.

Indexed as

AnophelesInsecticide ResistanceInsecticide-Treated BednetsMosquito ControlMosquito VectorsAnimalsBeninFemaleMalariaInsecticideMalariaNetsPyrethroidResistance

Identifiers

PMID28549431
PMCPMC5446701
OpenAlexW2619010884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.