Evidence map›Paper›PMID 28549075›Full record

ArticleBrain : a journal of neurology2017

Age of onset in Huntington's disease is influenced by CAG repeat variations in other polyglutamine disease-associated genes.

Geerte Stuitje, Martine J van Belzen, Sarah L Gardiner, Willeke M C van Roon-Mom, Merel W Boogaard, REGISTRY Investigators of the European Huntington Disease Network, Sarah J Tabrizi, Raymund A C Roos, N A Aziz

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Brain : a journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Movement Disorders in Hereditary Cerebellar Ataxia.Movement disorders clinical practice · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Co-expression Patterns betweenFrontiers in molecular neuroscience · 2017
    Article
  10. A Co-occurrence of Trinucleotide Repeat Disorders.Movement disorders clinical practice
    Article
  11. The Missing Link in Polyglutamine Diseases.Movement disorders clinical practice
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Geerte StuitjeDepartment of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.
Martine J van BelzenDepartment of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Sarah L GardinerDepartment of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.
Willeke M C van Roon-MomDepartment of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
Merel W BoogaardDepartment of Clinical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.
REGISTRY Investigators of the European Huntington Disease Network
Sarah J TabriziDepartment of Neurodegenerative Disease, UCL Huntington's Disease Centre, University College London Institute of Neurology, London, UK.
Raymund A C RoosDepartment of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.
N A AzizDepartment of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

Funding

Wellcome Trust 200181/Z/15/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Huntington DiseaseSpinocerebellar AtaxiasHumansPeptidesPeptidespolyglutamine

Identifiers

PMID28549075

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.