ArticlePloS one2017
The atherogenic index of plasma and the risk of mortality in incident dialysis patients: Results from a nationwide prospective cohort in Korea.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Prognostic Value of Inflammatory Indices and the Advanced Lung Cancer Inflammation Index (ALI) for Survival Outcomes in Hemodialysis Patients.Medicina (Kaunas, Lithuania) · 2026Article
- Insulin Resistance and Atherogenic Dyslipidemia Drive Cardiac Remodeling and Cardiovascular Events After Kidney Transplantation.Journal of clinical medicine · 2026Article
- The association between global diet quality index with novel cardiovascular risk factors and problem areas in diabetes scale (PAID) among patients with type 2 diabetes mellitus.Journal of diabetes and metabolic disorders · 2025Article
- The association between triglyceride-glucose index and all-cause/cardiovascular mortality in patients with different glucose metabolism statuses.Cardiovascular diabetology · 2025Article
- Long-term cardiometabolic and bone health consequences of ketogenic diet in children with refractory epilepsy.Italian journal of pediatrics · 2025Article
- Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population.Journal of clinical medicine · 2025Article
- Associations of the atherogenic index of plasma with 28-day in-hospital mortality in patients with acute myocardial infarction: a retrospective cohort study from the eICU.Lipids in health and disease · 2025Article
- The association between the atherogenic index of plasma and all-cause mortality in patients undergoing peritoneal dialysis: a multicenter cohort study.Lipids in health and disease · 2025Article
- Association between the atherogenic index of plasma and mortality in the chronic kidney disease population: evidence from NHANES.Frontiers in medicine · 2025Article
- Article
- The Predictive Value of Atherogenic Index of Plasma, Non- High Density Lipoprotein Cholesterol (Non-HDL-C), Non-HDL-C/HDL-C, and Lipoprotein Combine Index for Stroke Incidence and Prognosis in Maintenance Hemodialysis Patients.Clinical interventions in aging · 2024Article
- Atherogenic index of plasma: a new indicator for assessing the short-term mortality of patients with acute decompensated heart failure.Frontiers in endocrinology · 2024Article
- How is healthy eating index-2015 related to risk factors for cardiovascular disease in patients with type 2 diabetes.Frontiers in nutrition · 2023Article
- Atherogenic index of plasma is associated with epicardial adipose tissue volume assessed on coronary computed tomography angiography.Scientific reports · 2022Article
- Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis.Trends in endocrinology and metabolism: TEM · 2021Review
- The Comparison of Antioxidant Effect of Aspirin, Metformin, Atorvastatin and Captopril Co-administration in the Heart and Kidney Tissues of Diabetic Rats.Iranian journal of pharmaceutical research : IJPR · 2021Article
- Prognostic impact of the atherogenic index of plasma in type 2 diabetes mellitus patients with acute coronary syndrome undergoing percutaneous coronary intervention.Lipids in health and disease · 2020Article
- Atherogenic index of plasma predicts cerebrovascular accident occurrence in antineutrophil cytoplasmic antibody-associated vasculitis.Lipids in health and disease · 2020Article
- The atherogenic index of plasma and its impact on recanalization of chronic total occlusion.Cardiology journal · 2020Article
- Dyslipidemia and Intraperitoneal Inflammation Axis in Peritoneal Dialysis Patients: A Cross-Sectional Pilot Study.Kidney diseases (Basel, Switzerland) · 2020Article
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe atherogenic index of plasma (AIP), which is the logarithmic ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C), had a linear relationship with clinical outcomes in the general population. However, the association of each lipid profile, TG and HDL-C, with survival was not straightforward in dialysis patients. This non-linear association led us to further investigate the prognostic impact of the AIP in these patients.
methodsFrom a nationwide prospective cohort, 1,174 incident dialysis patients were included. Patients were categorized into quintiles according to the AIP. An independent association of the AIP with all-cause and cardiovascular mortality was determined.
resultsDuring a mean follow-up duration of 33.2 months, 170 patients (14.5%) died, and cardiovascular death was observed in 55 patients (4.7%). Multivariate Cox analyses revealed that the lowest (quintile 1, hazard ratio [HR] = 1.76, 95% confidence interval [CI] = 1.02-3.03) and the highest (quintile 5, HR = 2.15, 95% CI = 1.26-3.65) AIP groups were significantly associated with higher all-cause mortality compared to patients in quintile 3 (reference group). In terms of cardiovascular mortality, only the highest AIP group (quintile 5, HR = 2.59, 95% CI = 1.06-6.34) was significantly associated with increased risk of mortality. Sensitivity analyses showed that a U-shaped association between the AIP and all-cause mortality remained significant in non-diabetic and underweight to normal body mass index patients.
conclusionsBoth the highest and the lowest AIP groups were independently associated with all-cause mortality, showing a U-shaped association. It suggested further studies are needed to identify targets and subgroups that can benefit from intervention of the AIP in incident dialysis patients.
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