ArticleMedical physics2017
Fast computation of full density matrix of multispin systems for spatially localized in vivo magnetic resonance spectroscopy.
Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Effect of naltrexone pretreatment on ketamine-induced glutamatergic activity and symptoms of depression: a randomized crossover study.Nature medicine · 2025Trial
- Simultaneous edited MRS of GABA, glutathione, and ethanol.NMR in biomedicine · 2020Trial
- Trial
- GABA+-Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework.Magnetic resonance in medicine · 2026Article
- Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and TMagnetic resonance in medicine · 2026Article
- Developmental trajectories of glutamate and the variable clinical course of ADHD in youth.Translational psychiatry · 2026Article
- Simultaneous in vivo detection of spectrally resolved glutamate, glutamine, and glutathione at 3 T with NAA-aspartyl editing and echo-time optimization.Magnetic resonance in medicine · 2026Article
- SMART MRS: A Simulated MEGA-PRESS ARTifacts toolbox for GABA-edited MRS.Magnetic resonance in medicine · 2025Article
- In vivo GABA detection by single-pulse editing with one shot.Magnetic resonance in medicine · 2025Article
- Enhanced detection of glutamate via transverse relaxation encoding with narrowband decoupling in the human brain.Magnetic resonance in medicine · 2025Article
- Chemical shift and relaxation regularization improve the accuracy ofMagnetic resonance in medicine · 2025Article
- WAND: Wavelet Analysis-Based Neural Decomposition of MRS Signals for Artifact Removal.NMR in biomedicine · 2025Article
- Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for advanced MRS.Journal of neuroscience methods · 2024Article
- Metabolic coupling between glutamate and N-acetylaspartate in the human brain.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Results of the 2023 ISBI challenge to reduce GABA-edited MRS acquisition time.Magma (New York, N.Y.) · 2024Article
- Impaired striatal glutamate/GABA regulation in violent offenders with antisocial personality disorder and psychopathy.Molecular psychiatry · 2024Article
- Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS.bioRxiv : the preprint server for biology · 2024Article
- Glutamate measurements using edited MRS.Magnetic resonance in medicine · 2024Article
- sLASER and PRESS perform similarly at revealing metabolite-age correlations at 3 T.Magnetic resonance in medicine · 2024Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposeNumerical simulations of three-dimensionally localized MRS spectra have been very time consuming for multispin systems because the current state-of-the-art method requires computation of a large ensemble of spins pixel-by-pixel in three dimensional space. This paper describes a highly accelerated technique for computing spatially localized MRS spectra using the full solution to the Liouville-von Neumann equation.
methodsThe time evolution of spatially localized multispin density matrix as the full solution to the Liouville-von Neumann equation was analyzed. A new technique based on one dimensional spatial projection of the full density matrix was proposed. This method was implemented using a computer program written in Java language.
resultsThe MRS spectra calculated using the new method were found to be identical to conventional three-dimensional simulation for the same digitization of the voxel while the new method reduced computation time by orders of magnitude and led to not only improved speed but also accuracy. Applications of the new method to phantom studies of multispin systems and quantification of in vivo MRS spectra of brain were demonstrated.
conclusionThe dramatically enhanced computational efficiency makes accurate simulation of localized MRS spectra highly accessible for calculating basis sets for spectral quantification and for optimizing pulse sequences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.