ReviewNature reviews. Neurology2017
Current controversies in brain death determination.
Review in Nature reviews. Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review to assess the possibility of return of cerebral and cardiac activity after normothermic regional perfusion for donors after circulatory death.The British journal of surgery · 2019Pooled it
- A Qualitative Analysis of Physician Communication During Brain Death Conversations: Dead With a Heartbeat.Neurology. Clinical practice · 2025Article
- Article
- Navigating disagreement and conflict in the context of a brain-based definition of death.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Review
- Functional bioengineered models of the central nervous system.Nature reviews bioengineering · 2023Review
- "Death as the One Great Certainty": ethical implications of children with irreversible cardiorespiratory failure and dependence on extracorporeal membrane oxygenation.Frontiers in pediatrics · 2023Article
- Article
- Cerebral blood vessels and perfusion in the pediatric brain death: five cases studied by neuroimaging.Neuroradiology · 2022Article
- Revise the Uniform Determination of Death Act to Align the Law With Practice Through Neurorespiratory Criteria.Neurology · 2022Article
- A scoping review of the perceptions of death in the context of organ donation and transplantation.BMC medical ethics · 2021Article
- Pediatric brain death certification: a narrative review.Translational pediatrics · 2021Review
- Atypical Pupil Reactions in Brain Dead Patients.Brain sciences · 2021Article
- Brain death and management of the potential donor.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Review
- Brain beats heart: a cross-cultural reflection.Brain : a journal of neurology · 2021Article
- Religious Accommodation in Bioethics and the Practice of Medicine.The Journal of medicine and philosophy · 2021Article
- Does the Uniform Determination of Death Act Need to Be Revised?The Linacre quarterly · 2020Article
- Refinements in the Organism as a Whole Rationale for Brain Death.The Linacre quarterly · 2019Article
- Epidemiology of childhood death in Australian and New Zealand intensive care units.Intensive care medicine · 2019Article
- The observation period after clinical brain death diagnosis according to ancillary tests: differences between supratentorial and infratentorial brain injury.Journal of neurology · 2019Observational
- Epidemiology of Brain Death in Pediatric Intensive Care Units in the United States.JAMA pediatrics · 2019Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the concept of brain death is accepted by the majority of physicians, lawyers, ethicists and society at large, controversies about determination of death by neurological criteria persist, and often reach the public eye. In this article, we examine four prominent controversial brain death cases from 2013-2016. We review current controversies, including protocol variability, recognition of the American Academy of Neurology (AAN) criteria for brain death as an accepted medical standard, and management of objections to discontinuation of organ support after determination of brain death. Brain death remains conceptually and legally valid, and it is vital that these issues are solved. We argue that medical societies and governmental regulatory bodies must support the AAN criteria in order to decrease protocol variability, and must fully endorse the validity of these criteria as accepted medical standards.
Indexed as
Identifiers
28548107What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.