Evidence map›Paper›PMID 28548102›Full record

ArticleNature communications2017

Replicating viral vector platform exploits alarmin signals for potent CD8

Sandra M Kallert, Stephanie Darbre, Weldy V Bonilla, Mario Kreutzfeldt, Nicolas Page, Philipp Müller, Matthias Kreuzaler, Min Lu, Stéphanie Favre, Florian Kreppel and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
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  12. The Role of Estrogen in Brain MicroRNAs Regulation.Advanced pharmaceutical bulletin · 2024
    Review
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  15. Article
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  18. A replicating LCMV-based vaccine for the treatment of solid tumors.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Sandra M KallertDivision of Experimental Virology, Department of Biomedicine, University of Basel, Petersplatz 10, 4009 Basel, Switzerland.
Stephanie DarbreDepartement de Pathologie et Immunologie, Centre Médical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland.
Weldy V BonillaDivision of Experimental Virology, Department of Biomedicine, University of Basel, Petersplatz 10, 4009 Basel, Switzerland.
Mario KreutzfeldtDepartement de Pathologie et Immunologie, Centre Médical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland.
Nicolas PageDepartement de Pathologie et Immunologie, Centre Médical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland.
Philipp MüllerDepartment of Biomedicine, University Hospital and University of Basel, Hebelstr. 20, 4031 Basel, Switzerland.
Matthias KreuzalerDepartment of Biomedicine, University Hospital and University of Basel, Hebelstr. 20, 4031 Basel, Switzerland.
Min LuDivision of Experimental Virology, Department of Biomedicine, University of Basel, Petersplatz 10, 4009 Basel, Switzerland.
Stéphanie FavreDepartment of Biochemistry, Center for Immunity and Infection Lausanne, University of Lausanne, Chemin des Boveresses 144, 1066 Epalinges, Switzerland.
Florian KreppelWitten/Herdecke University (UW/H), Faculty of Health/School of Medicine, Stockumer Str. 10, 58453 Witten, Germany.
Max LöhningExperimental Immunology and Osteoarthritis Research, Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Sanjiv A LutherDepartment of Biochemistry, Center for Immunity and Infection Lausanne, University of Lausanne, Chemin des Boveresses 144, 1066 Epalinges, Switzerland.
Alfred ZippeliusDepartment of Biomedicine, University Hospital and University of Basel, Hebelstr. 20, 4031 Basel, Switzerland.
Doron MerklerDepartement de Pathologie et Immunologie, Centre Médical Universitaire, University of Geneva, 1 rue Michel Servet, 1211 Geneva, Switzerland.
Daniel D PinschewerDivision of Experimental Virology, Department of Biomedicine, University of Basel, Petersplatz 10, 4009 Basel, Switzerland.ORCID 0000-0002-1594-3189
University of Basel · CHUniversity of Geneva · CHUniversity of Lausanne · CHGerman Rheumatism Research Centre · DEWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTL

Indexed as

AlarminsAnimalsAntigens, NeoplasmCancer VaccinesCell Line, TumorDendritic CellsGene Expression ProfilingGenetic EngineeringGenetic VectorsHEK293 CellsHumansImmunotherapyInterleukin-33Lymphocyte ActivationLymphocytic choriomeningitis virusMesocricetusAlarminsAntigens, NeoplasmCancer VaccinesIl33 protein, mouseInterleukin-33Vaccines, Live, Unattenuated

Identifiers

PMID28548102
PMCPMC5458557
OpenAlexW2617873219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.