Evidence map›Paper›PMID 28547918›Full record

ArticleObesity (Silver Spring, Md.)2017

Exercise with weight loss improves adipose tissue and skeletal muscle markers of fatty acid metabolism in postmenopausal women.

Heidi K Ortmeyer, Andrew P Goldberg, Alice S Ryan

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Heidi K OrtmeyerDepartment of Medicine, Division of Gerontology and Geriatric Medicine at the University of Maryland School of Medicine, Baltimore, Maryland, USA.
Andrew P GoldbergDepartment of Medicine, Division of Gerontology and Geriatric Medicine at the University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alice S RyanDepartment of Medicine, Division of Gerontology and Geriatric Medicine at the University of Maryland School of Medicine, Baltimore, Maryland, USA.
Geriatric Research Education and Clinical Center · USUniversity of Maryland, Baltimore · USVA Maryland Health Care System · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Zonulin Antibodies in Intestinal Permeabilitiy in IDDMM01RR016500 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI ONUKWUGHA, EBERECHUKWU · 2002 to 2009
$20.2M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
UPPER EXTREMITY TRAINING FOR CHRONIC STROKEP60AG012583 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLDBERG, ANDREW P · 1994 to 2005
$7.8M
Race, Lipoprotein Lipase and Obesity after MenopauseR01AG020116 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLDBERG, ANDREW P · 2003 to 2007
$2.2M
Diet and Exercise: Race, Postmenopause and MetabolismR01AG019310 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RYAN, ALICE S. · 2001 to 2005
$1.5M
NCRR NIH HHS M01 RR016500NIA NIH HHS P30 AG028747NIA NIH HHS P60 AG012583NIA NIH HHS R01 AG019310NIA NIH HHS R01 AG020116NIDDK NIH HHS P30 DK072488
6 · The paper itself

Abstract

objectiveThe effects of 6-month weight loss (WL) versus aerobic exercise training (AEX)+WL on fat and skeletal muscle markers of fatty acid metabolism were determined in normal (NGT) and impaired (IGT) glucose tolerant African-American and Caucasian postmenopausal women with overweight/obesity.

methodsFat (gluteal and abdominal) lipoprotein lipase (LPL), skeletal muscle LPL, acyl-CoA synthase (ACS), ß-hydroxacyl-CoA dehydrogenase, carnitine palmitoyltransferase (CPT-1), and citrate synthase (CS) activities were measured at baseline (n = 104) and before and after WL (n = 34) and AEX+WL (n = 37).

resultsAfter controlling for age and race, muscle LPL and CPT-1 were lower in IGT, and the ratios of fat/muscle LPL activity were higher in IGT compared to NGT. Muscle LPL was related to insulin sensitivity (M value) and inversely related to G

conclusionsSix-month AEX+WL, and not WL alone, is capable of enhancing skeletal muscle fatty acid metabolism in postmenopausal African-American and Caucasian women with NGT, IGT, and overweight/obesity.

Indexed as

ExerciseLipid MetabolismWeight Loss3-Hydroxyacyl-CoA DehydrogenaseAgedBiomarkersBlack or African AmericanCarnitine O-PalmitoyltransferaseCitrate (si)-SynthaseCoenzyme A LigasesFemaleHumansInsulinInsulin ResistanceLipoprotein LipaseMiddle Aged3-Hydroxyacyl-CoA DehydrogenaseBiomarkersCarnitine O-PalmitoyltransferaseCitrate (si)-SynthaseCoenzyme A LigasesInsulinLipoprotein Lipase

Identifiers

PMID28547918
PMCPMC5487288
OpenAlexW2619170294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.