ArticleJournal of anatomy2017
Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography.
Article in Journal of anatomy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Ontogeny and Homology of the Shoulder Joint and Forelimb Muscles in Frogs and Toads (Lissamphibia: Anura).Journal of morphology · 2026Article
- Bone and Cartilage Staining for Skeletal Preparations.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Efficient Techniques for Comprehensive Sampling of Accessible Tissues in Adult Xenopus.Journal of visualized experiments : JoVE · 2025Article
- Functional anatomy of the wing muscles of the Egyptian fruit bat (Rousettus aegyptiacus) using dissection and diceCT.Journal of anatomy · 2025Article
- A new analogous organ in bony fishes and amphibians: an anatomical structure related with the cerebrospinal fluid circulation.Scientific reports · 2025Article
- The SmARTR pipeline: A modular workflow for the cinematic rendering of 3D scientific imaging data.iScience · 2024Article
- Comparative muscle anatomy of the anuran pelvis and hindlimb in relation to locomotor mode.Journal of anatomy · 2024Article
- Techniques for Rapidly Sampling Six Crucial Organs in Adult Xenopus.Journal of visualized experiments : JoVE · 2024Article
- Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging.GigaScience · 2024Article
- Effective Rapid Blood Perfusion inbioRxiv : the preprint server for biology · 2023Article
- Morphological, acoustic and genetic identification of a reproducing population of the invasive African clawed frogZooKeys · 2023Article
- Microvascular anatomy of the non-lobulated liver of adult Xenopus laevis: A scanning electron microscopic study of vascular casts.Anatomical record (Hoboken, N.J. : 2007) · 2022Article
- Mid-Tibiofibular Amputation as a Method of Terminal Blood Collection inJournal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Digital dissection of the head of the frogs Calyptocephalella gayi and Leptodactylus pentadactylus with emphasis on the feeding apparatus.Journal of anatomy · 2021Article
- The morphology and evolution of chondrichthyan cranial muscles: A digital dissection of the elephantfish Callorhinchus milii and the catshark Scyliorhinus canicula.Journal of anatomy · 2021Article
- Brain size variation along altitudinal gradients in the Asiatic Toad (Ecology and evolution · 2021Article
- A digital dissection of two teleost fishes: comparative functional anatomy of the cranial musculoskeletal system in pike (Esox lucius) and eel (Anguilla anguilla).Journal of anatomy · 2019Article
- Article
- Digital dissection of the head of the rock dove (Zoological letters · 2019Article
- Three-Dimensional Portable Document Format (3D PDF) in Clinical Communication and Biomedical Sciences: Systematic Review of Applications, Tools, and Protocols.JMIR medical informatics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The African clawed frog, Xenopus laevis, is one of the most widely used model organisms in biological research. However, the most recent anatomical description of X. laevis was produced nearly a century ago. Compared with other anurans, pipid frogs - including X. laevis - exhibit numerous unusual morphological features; thus, anatomical descriptions of more 'typical' frogs do not detail many aspects of X. laevis skeletal and soft-tissue morphology. The relatively new method of using iodine-based agents to stain soft tissues prior to high-resolution X-ray imaging has several advantages over gross dissection, such as enabling dissection of very small and fragile specimens, and preserving the three-dimensional topology of anatomical structures. Here, we use contrast-enhanced computed tomography to produce a high-resolution three-dimensional digital dissection of a post-metamorphic X. laevis to successfully visualize: skeletal and muscular anatomy; the nervous, respiratory, digestive, excretory and reproductive systems; and the major sense organs. Our digital dissection updates and supplements previous anatomical descriptions of this key model organism, and we present the three-dimensional data as interactive portable document format (PDF) files that are easily accessible and freely available for research and educational purposes. The data presented here hold enormous potential for applications beyond descriptive purposes, particularly for biological researchers using this taxon as a model organism, comparative anatomy and biomechanical modelling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.