Evidence map›Paper›PMID 28547728›Full record

ArticleWorld journal of microbiology & biotechnology2017

The protective effect of a novel antioxidant gene from Mycobacterium avium against nitrosative and oxidative stress in E. coli.

Shiyi He, Aiyan Wang, Xueping Ning, Dongjun Yang, Min Ling

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shiyi HeKey Laboratory of Biological Molecular Medicine Research of Guangxi University, Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, 530021, People's Republic of China.
Aiyan WangKey Laboratory of Biological Molecular Medicine Research of Guangxi University, Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, 530021, People's Republic of China.
Xueping NingKey Laboratory of Biological Molecular Medicine Research of Guangxi University, Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, 530021, People's Republic of China.
Dongjun YangKey Laboratory of Biological Molecular Medicine Research of Guangxi University, Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, 530021, People's Republic of China.
Min LingKey Laboratory of Biological Molecular Medicine Research of Guangxi University, Department of Biochemistry and Molecular Biology, Guangxi Medical University, Nanning, 530021, People's Republic of China. lingmin70@163.com.
Guangxi Medical University · CNGuangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) is an important host defense mechanism in response to infection by Mycobacterium tuberculosis. A variety of genes have been implicated in resistance to ROI and RNI, including noxR1. However, studies in Mycobacterium avium, an important pathogen among nontuberculous mycobacteria, are limited. We aim to investigate the role of a novel gene cloned from M. avium with high similarity to noxR1, noA, in resistance against RNI and ROI in M. tuberculosis. After subcloning noA into vector for expression in E. coli, we performed survival rate analysis in the bacteria transformed with noA (pET-noA) and without noA (pET-his) after exposure to nitrosative stresses by S-nitrosoglutathione (GSNO) and sodium nitrite, and oxidative stresses by H

Indexed as

AntioxidantsBacterial ProteinsBase SequenceCloning, MolecularEscherichia coliGene Expression Regulation, BacterialGenes, BacterialHydrogen PeroxideMycobacterium aviumMycobacterium tuberculosisNitrosative StressOxidative StressReactive Oxygen SpeciesSequence HomologyS-NitrosoglutathioneSodium NitriteAntioxidantsBacterial ProteinsHydrogen PeroxideReactive Oxygen SpeciesS-NitrosoglutathioneSodium NitriteAntioxidant geneMycobacterium aviumResistanceRNIROI

Identifiers

PMID28547728
OpenAlexW2619739790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.