Evidence map›Paper›PMID 28547660›Full record

Trial reportAnnals of biomedical engineering2017

Rib Geometry Explains Variation in Dynamic Structural Response: Potential Implications for Frontal Impact Fracture Risk.

Michelle M Murach, Yun-Seok Kang, Samuel D Goldman, Michelle A Schafman, Stephen H Schlecht, Kevin Moorhouse, John H Bolte, Amanda M Agnew

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Annals of biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Functionally graded 3D printed plates for rib fracture fixation.Clinical biomechanics (Bristol, Avon) · 2024
    Article
  7. Cross-sectional properties of rib geometry from an adult population.Frontiers in bioengineering and biotechnology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michelle M MurachInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA.
Yun-Seok KangInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA.
Samuel D GoldmanInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA.
Michelle A SchafmanInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA.
Stephen H SchlechtDepartment of Orthopaedic Surgery, University of Michigan, Biomedical Sciences Research Building, Ann Arbor, MI, 48109, USA.
Kevin MoorhouseNational Highway Traffic and Safety Administration, Vehicle Research and Test Center, East Liberty, OH, 43074, USA.
John H BolteInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA.
Amanda M AgnewInjury Biomechanics Research Center, The Ohio State University, 2063 Graves Hall, 333 W. 10th Ave, Columbus, OH, 43210, USA. amanda.agnew@osumc.edu.
The Ohio State University · USNational Highway Traffic Safety Administration · USUniversity of Michigan–Ann Arbor · US

Funding

Tissue Engineering and RegenerationT32DE007057 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID H. KOHN · 1985 to 2026
$17.3M
National Highway Traffic Safety Administration DTNH2214D00348LNIDCR NIH HHS T32 DE007057
6 · The paper itself

Abstract

The human thorax is commonly injured in motor vehicle crashes, and despite advancements in occupant safety rib fractures are highly prevalent. The objective of this study was to quantify the ability of gross and cross-sectional geometry, separately and in combination, to explain variation of human rib structural properties. One hundred and twenty-two whole mid-level ribs from 76 fresh post-mortem human subjects were tested in a dynamic frontal impact scenario. Structural properties (peak force and stiffness) were successfully predicted (p < 0.001) by rib cross-sectional geometry obtained via direct histological imaging (total area, cortical area, and section modulus) and were improved further when utilizing a combination of cross-sectional and gross geometry (robusticity, whole bone strength index). Additionally, preliminary application of a novel, adaptive thresholding technique, allowed for total area and robusticity to be measured on a subsample of standard clinical CT scans with varied success. These results can be used to understand variation in individual rib response to frontal loading as well as identify important geometric parameters, which could ultimately improve injury criteria as well as the biofidelity of anthropomorphic test devices (ATDs) and finite element (FE) models of the human thorax.

Indexed as

Models, BiologicalRib FracturesRibsTomography, X-Ray ComputedAdolescentAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedCross-sectional geometryFracture riskRibRobusticityStiffnessThorax

Identifiers

PMID28547660
PMCPMC5860670
OpenAlexW2618222517

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.