Evidence map›Paper›PMID 28547531›Full record

ArticleMolecular neurobiology2018

Neonatal Hyperoxia Perturbs Neuronal Development in the Cerebellum.

Till Scheuer, Yuliya Sharkovska, Victor Tarabykin, Katharina Marggraf, Vivien Brockmöller, Christoph Bührer, Stefanie Endesfelder, Thomas Schmitz

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Targeting adenosine APurinergic signalling · 2025
    Review
  6. Cerebellar Development and the Burden of Prematurity.Cerebellum (London, England) · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Till ScheuerDepartment for Neonatology, Charité University Medical Center, Berlin, Germany. Till.Scheuer@charite.de.ORCID http://orcid.org/0000-0002-9465-7200
Yuliya SharkovskaDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Victor TarabykinInstitute for Cell and Neurobiology, Center for Anatomy, Charité University Medical Center, Berlin, Germany.
Katharina MarggrafDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Vivien BrockmöllerDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Christoph BührerDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Stefanie EndesfelderDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Thomas SchmitzDepartment for Neonatology, Charité University Medical Center, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DE

Funding

Deutsche Forschungsgemeinschaft SCHM3007/2-1Deutsche Forschungsgemeinschaft SCHM3007/3-2
6 · The paper itself

Abstract

Impaired postnatal brain development of preterm infants often results in neurological deficits. Besides pathologies of the forebrain, maldeveolopment of the cerebellum is increasingly recognized to contribute to psychomotor impairments of many former preterm infants. However, causes are poorly defined. We used a hyperoxia model to define neonatal damage in cerebellar granule cell precursors (GCPs) and in Purkinje cells (PCs) known to be essential for interaction with GCPs during development. We exposed newborn rats to 24 h 80% O

Indexed as

NeurogenesisAnimalsAnimals, NewbornCell CountCell DeathCell ProliferationCerebellumDendritesDoublecortin ProteinGene Expression Regulation, DevelopmentalHedgehog ProteinsHyperoxiaNeuronsPurkinje CellsRats, WistarDcx protein, ratDoublecortin ProteinHedgehog ProteinsCerebellumGranule cellsHyperoxiaPreterm infantsPurkinje cellsSonic hedgehog

Identifiers

PMID28547531
OpenAlexW2619737660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.