Evidence map›Paper›PMID 28547385›Full record

ReviewArchives of virology2017

Flavonoids: promising natural compounds against viral infections.

Hovakim Zakaryan, Erik Arabyan, Adrian Oo, Keivan Zandi

Open access · bronzeAbstract readReview
In one paragraph

Review in Archives of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 2 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

199 citing papers in PubMed, 2 syntheses or guidelines pooled it, 517 citations in OpenAlex.

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  15. Current pharmaceutical biotechnology · 2026
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139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Hovakim ZakaryanGroup of Antiviral Defense Mechanisms, Institute of Molecular Biology of NAS RA, Hasratyan 7, 0014, Yerevan, Armenia. h_zakaryan@mb.sci.am.
Erik ArabyanGroup of Antiviral Defense Mechanisms, Institute of Molecular Biology of NAS RA, Hasratyan 7, 0014, Yerevan, Armenia.
Adrian OoDepartment of Medical Microbiology, Faculty of Medicine, Tropical Infectious Disease Research and Education Center (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
Keivan ZandiDepartment of Medical Microbiology, Faculty of Medicine, Tropical Infectious Disease Research and Education Center (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
National Academy of Sciences of Armenia · AMEmory University · USUniversity of Malaya · MY

Funding

RA MES State Committee of Science 15RF-081, 16YR-1F064
6 · The paper itself

Abstract

Flavonoids are widely distributed as secondary metabolites produced by plants and play important roles in plant physiology, having a variety of potential biological benefits such as antioxidant, anti-inflammatory, anticancer, antibacterial, antifungal and antiviral activity. Different flavonoids have been investigated for their potential antiviral activities and several of them exhibited significant antiviral properties in in vitro and even in vivo studies. This review summarizes the evidence for antiviral activity of different flavonoids, highlighting, where investigated, the cellular and molecular mechanisms of action on viruses. We also present future perspectives on therapeutic applications of flavonoids against viral infections.

Indexed as

AnimalsAntiviral AgentsFlavonoidsHumansMolecular StructurePlantsVirus DiseasesAntiviral AgentsFlavonoids

Identifiers

PMID28547385
PMCPMC7087220
OpenAlexW2618085212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.