Evidence map›Paper›PMID 28547175›Full record

Observational studyEuropean journal of nuclear medicine and molecular imaging2017

Influence of body mass index and type of low-level exercise on the side effect profile of regadenoson.

Carlos Salgado-Garcia, Amelia Jimenez-Heffernan, Juana Lopez-Martin, Manuela Molina-Mora, Tarik Aroui, Elena Sanchez de Mora, Carlos Ramos-Font, Francisco Rivera de Los Santos, Carlos Ruiz-Frutos

Abstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carlos Salgado-GarciaDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain. carlosd.salgado.sspa@juntadeandalucia.es.ORCID http://orcid.org/0000-0002-1571-6891
Amelia Jimenez-HeffernanDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Juana Lopez-MartinDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Manuela Molina-MoraDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Tarik ArouiDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Elena Sanchez de MoraDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Carlos Ramos-FontDepartment of Nuclear Medicine, Hospital Juan Ramon Jimenez. Complejo Hospitalario Universitario de Huelva, Ronda Norte, s/n, 21005, Huelva, Spain.
Francisco Rivera de Los SantosArea of Methodology of Behavioural Sciences, University of Seville, 41018, Seville, Spain.
Carlos Ruiz-FrutosDepartment of Environmental and Public Health, University of Huelva, 21071, Huelva, Spain.
Hospital Juan Ramón Jiménez · ESUniversidad de Huelva · ESUniversidad de Sevilla · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRegadenoson, an A

methodsThree hundred and fifty-six patients (46.1% men, mean age 67.7±10.7 years, range 31-90 years) underwent regadenoson stress testing combined with low-level exercise. Subjects were classified according to BMI as normal, overweight, or obese, and the type of low-level exercise performed as walking on the treadmill (TE group, n=190) or forcefully swinging legs while sitting (SS group, n=166). Patients' demographics, medical history, clinical symptoms during stress, changes in ECG, oxygen saturation (SatO

resultsGroups were comparable (p=ns) with regard to cardiovascular risks factors. The incidence of side effects was similar across BMI (p=ns), although the TE patients showed improved profiles over those with SS exercise, with a significantly lower incidence of flushing, dizziness and nausea/gastrointestinal discomfort (12.9% vs. 28.4%; 19.9% vs. 33.4%; 11.4% vs. 19.2%, respectively; all p<0.05). Regarding the hemodynamic response, we did not observe significant changes in SBP and HR after regadenoson administration across BMI categories. Comparing the TE and SS groups, no significant changes were observed in SBP, but there was a higher increase in HR in the TE group (p<0.05).

conclusionsRegadenoson in combination with low-level exercise is safe and well tolerated over a wide range of BMI, with TE exercise showing a better side effect profile than SS.

Indexed as

Body Mass IndexExerciseAdenosine A2 Receptor AgonistsAdultAgedAged, 80 and overExercise TestFemaleHemodynamicsHumansMaleMiddle AgedMyocardial Perfusion ImagingPurinesPyrazolesAdenosine A2 Receptor AgonistsPurinesPyrazolesregadenosonBody mass indexLow-level exerciseMyocardial perfusion imagingRegadenosonSafetySide effects

Identifiers

PMID28547175
OpenAlexW2619262157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.