Evidence map›Paper›PMID 28546933›Full record

ArticleInternational journal of ophthalmology2017

Correlation of neutrophil/lymphocyte and platelet/lymphocyte ratio with visual acuity and macular thickness in age-related macular degeneration.

Elvan Alper Sengul, Ozgur Artunay, Alev Kockar, Ceyda Afacan, Rifat Rasier, Palmet Gun, Nazli Gul Yalcin, Erdal Yuzbasioglu

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Evaluating the effectiveness of inflammatory markers in pediatric open globe injury using a modified pediatric ocular trauma score.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
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  20. Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios in Normal Tension Glaucoma.Medical hypothesis, discovery & innovation ophthalmology journal · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elvan Alper SengulOphthalmology Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.
Ozgur ArtunayOphthalmology Department, Haydarpasa Numune Training and Research Hospital, Istanbul 34668, Turkey.
Alev KockarOphthalmology Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.
Ceyda AfacanDepartment of Statistics, Mimar Sinan Fine Arts University, Istanbul 34427, Turkey.
Rifat RasierOphthalmology Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.
Palmet GunBiochemistry Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.
Nazli Gul YalcinOphthalmology Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.
Erdal YuzbasiogluOphthalmology Department, Medical Faculty, Istanbul Bilim University, Istanbul 34381, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the place of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in the diagnosis of and prognosis for neovascular age-related macular degeneration (AMD).

methodsOne hundred AMD patients and 100 healthy controls were included in the study. Blood samples were obtained from the venous blood, which is used for routine analysis, and these samples were subjected to complete blood count. NLR was defined as the neutrophil count divided by the number of lymphocytes, and PLR was defined as the platelet count divided by the number of lymphocytes.

resultsNo statistically significant difference was observed between the two groups under consideration in terms of demographic features (

conclusionNLR and PLR levels are higher among neovascular AMD patients as compared to healthy control group. NLR and PLR levels were found to be inversely proportional to BCVA and directly proportional to CMT.

Indexed as

age-related macular degenerationinflammationneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratio

Identifiers

PMID28546933
PMCPMC5437464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.