Evidence map›Paper›PMID 28546918›Full record

ArticleInternational journal of ophthalmology2017

B cell receptor signaling pathway involved in benign lymphoepithelial lesions of the lacrimal gland.

Xiao-Na Wang, Xin Ge, Jing Li, Xiao Liu, Jian-Min Ma

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Inhibitory effect ofAnnals of translational medicine · 2022
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiao-Na WangBeijing Tongren Eye Center, Beijing Institute of Ophthal-mology, Beijing Tongren Hospital, Beijing Ophthalmology &Vision Science Key Lab, Capital Medical University, Beijing 100730, China.
Xin GeBeijing Tongren Eye Center, Beijing Institute of Ophthal-mology, Beijing Tongren Hospital, Beijing Ophthalmology &Vision Science Key Lab, Capital Medical University, Beijing 100730, China.
Jing LiBeijing Tongren Eye Center, Beijing Institute of Ophthal-mology, Beijing Tongren Hospital, Beijing Ophthalmology &Vision Science Key Lab, Capital Medical University, Beijing 100730, China.
Xiao LiuBeijing Tongren Eye Center, Beijing Institute of Ophthal-mology, Beijing Tongren Hospital, Beijing Ophthalmology &Vision Science Key Lab, Capital Medical University, Beijing 100730, China.
Jian-Min MaBeijing Tongren Eye Center, Beijing Institute of Ophthal-mology, Beijing Tongren Hospital, Beijing Ophthalmology &Vision Science Key Lab, Capital Medical University, Beijing 100730, China.
Beijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo detect the expression of B cell receptor signaling pathway (BCRSP) in lacrimal gland benign lymphoepithelial lesions (LGBLEL).

methodsGene microarray was used to compare whole-genome expression in lacrimal gland tissues from LGBLEL patients to tissues from orbital cavernous hemangioma (control tissues). Expression of BCRSP was confirmed by polymerase chain reaction (PCR) and immunohistochemistry.

resultsThe expression of 22 genes of the BCRSP increased significantly in LGBLEL patients. PCR analysis showed that

conclusionBCRSP might be involved in the pathogenesis of LGBLEL.

Indexed as

B cell receptor signaling pathwaybenign lymphoepithelial lesionlacrimal glandpathogenesis

Identifiers

PMID28546918
PMCPMC5437449
OpenAlexW2625417887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.