Evidence map›Paper›PMID 28546866›Full record

ArticleMilitary Medical Research2017

A diagnostic protocol designed for determining allergic causes in patients with blood eosinophilia.

Jean-François Magnaval, Guy Laurent, Noémie Gaudré, Judith Fillaux, Antoine Berry

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Military Medical Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06265870 (Comparison of Outcome Between Specific Anthelminthic Treatment According to Test Results and Empirical Anthelminthic Treatment in Eosinophilic Patient), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06265870 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Outcome Between Specific Anthelminthic Treatment According to Test Results and Empirical Anthelminthic Treatment in Eosinophilic Patient

TypeinterventionalSponsorPrince of Songkla UniversityRan2024 to 2025Enrolled700ConditionsEosinophiliaArmsAlbendazole, Ivermectin or albendazole
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. scFv against HSP60 ofDisease markers · 2020
    Article
  6. Human toxocariasis and atopy.Parasite (Paris, France) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jean-François MagnavalDepartment of Medical Parasitology, Faculty of Medicine, Toulouse University, 37 allees Jules-Guesde, Toulouse, France.ORCID 0000-0003-0423-7948
Guy LaurentDepartment of Hematology, Toulouse University Hospitals, Toulouse, France.
Noémie GaudréDepartment of Parasitology and Mycology, Toulouse University Hospitals, Toulouse, France.
Judith FillauxDepartment of Parasitology and Mycology, Toulouse University Hospitals, Toulouse, France.
Antoine BerryPurpan Center for Pathophysiology, INSERM UMR U1043, CNRS UMR 5282, Toulouse University, Toulouse, France.
Université Fédérale de Toulouse Midi-Pyrénées · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood eosinophilia is a common laboratory abnormality, and its characterization frequently represents a quandary for primary care physicians. Consequently, in France, specialists and particularly hematologists, often must investigate patients who present with blood eosinophilia that often, but not always, occurs because of allergic causes. Both the Departments of Hematology and Parasitology at Toulouse University Hospitals established a collaboration to rule out allergic causes of eosinophilia, particularly helminthiases, prior to initiating more sophisticated investigations.

methodsSince 2004, the authors employed the same protocol to investigate eosinophilic outpatients who attended the clinic of Parasitology at Toulouse University Hospitals, and they reported the performance of this diagnostic procedure that was designed to be rapid (no hospitalization required) and only moderately expensive.

resultsA total of 406 patients who presented with blood eosinophilia greater than 0.5 (×10

conclusionThis study underlines the need to investigate patients presenting with even moderate blood eosinophilia. The work-up that was employed appears to be efficient and versatile and may be used by any medical specialist, such as in hematology, infectious disease, or internal medicine departments, who needs to investigate eosinophilic patients and should initially rule out any etiology of allergic eosinophilia.

Indexed as

AdolescentAdultAgedAged, 80 and overChildClinical ProtocolsEosinophiliaFemaleFranceHumansHypersensitivityMaleMiddle AgedMycologyOccupational ExposureOutpatientsAllergyBlood eosinophiliaClassificationDiagnostic protocolHelminthiasesSecondary eosinophilias

Identifiers

PMID28546866
PMCPMC5440933
OpenAlexW2620253439

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.