ReviewVascular health and risk management2017
Pediatric ventricular assist devices: current challenges and future prospects.
Review in Vascular health and risk management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 79 citations in OpenAlex.
- Methodological development of a pneumatic artificial muscle-driven left ventricular simulator using interpretive structural modeling.PloS one · 2026Article
- Recent Developments in Ventricular Assist Device Therapy.Reviews in cardiovascular medicine · 2025Review
- Long-term kidney outcomes in pediatric continuous-flow ventricular assist device patients.Pediatric nephrology (Berlin, Germany) · 2024Article
- Pediatric mechanical circulatory support - a review.Indian journal of thoracic and cardiovascular surgery · 2023Review
- Machine learning based on computational fluid dynamics enables geometric design optimisation of the NeoVAD blades.Scientific reports · 2023Article
- An Up-to-Date Literature Review on Ventricular Assist Devices Experience in Pediatric Hearts.Life (Basel, Switzerland) · 2022Review
- Development of Inspired Therapeutics Pediatric VAD: Computational Analysis and Characterization of VAD V3.Cardiovascular engineering and technology · 2022Article
- Design and Computational Evaluation of a Pediatric MagLev Rotary Blood Pump.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2021Article
- Ethical and practical dilemmas in cardiac transplantation in infants: a literature review.European journal of pediatrics · 2021Review
- Kidney replacement therapy in pediatric patients on mechanical circulatory support: challenges for the pediatric nephrologist.Pediatric nephrology (Berlin, Germany) · 2021Review
- The role of ventricular assist device in children.Cardiovascular diagnosis and therapy · 2021Review
- Epidemiology and Outcomes of Acute Decompensated Heart Failure in Children.Circulation. Heart failure · 2020Article
- Implantation of a HeartMate 3 in a 13-Year-Old Child with Dilated Cardiomyopathy.Pediatric cardiology · 2020Article
- Paving a Road Home: Developing Education for a Pediatric Home-Going VAD Program.The journal of extra-corporeal technology · 2019Article
- A Quality Bundle to Support High-Risk Pediatric Ventricular Assist Device Implantation.Pediatric cardiology · 2019Observational
- An introduction to point-of-care testing in extracorporeal circulation and LVADs.Hematology. American Society of Hematology. Education Program · 2018Review
- Recommendations on the Indications for RBC Transfusion for the Critically Ill Child Receiving Support From Extracorporeal Membrane Oxygenation, Ventricular Assist, and Renal Replacement Therapy Devices From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Article
- Virtual reality-guided left ventricular assist device implantation in pediatric patient: Valuable presurgical tool.Annals of pediatric cardiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The field of mechanical circulatory support has made great strides in the preceding 2 decades. Although pediatric mechanical circulatory support has lagged behind that of adults, the gap between them is expected to close soon. The only device currently approved by the US Food and Drug Administration for use in children is the Berlin Heart EXCOR ventricular assist device (VAD). The prospective Berlin Heart Investigational Device Exemption Trial demonstrated good outcomes, such as bridge to transplantation or recovery, in ~90% of children supported with this device. However, a high incidence of hemorrhagic and thrombotic complications was also noted. As a result, pediatric centers have just started implanting adult intracorporeal continuous-flow devices in children. This paradigm shift has opened a new era in pediatric mechanical circulatory support. Whereas children on VAD were previously managed exclusively in hospital, therapeutic options such as outpatient management and even destination therapy have been becoming a reality. With continued miniaturization and technological refinements, devices currently in development will broaden the range of options available to children. The HeartMate 3 and HeartWare MVAD are two such compact VADs, which are anticipated to have great potential for pediatric use. Additionally, a pediatric-specific continuous-flow VAD, the newly redesigned Jarvik Infant 2015, is currently undergoing preclinical testing and is expected to undergo a randomized clinical trial in the near future. This review aims to discuss the challenges posed by the use of intracorporeal adult continuous-flow devices in children, as well as to provide our perspective on the future prospects of the field of pediatric VADs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.