Evidence map›Paper›PMID 28546747›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2017

The direct and indirect costs of managing chronic obstructive pulmonary disease in Greece.

Kyriakos Souliotis, Hara Kousoulakou, Georgios Hillas, Nikos Tzanakis, Michalis Toumbis, Theodoros Vassilakopoulos

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The economic burden of chronic obstructive pulmonary disease (COPD) in Europe: results from a systematic review of the literature.The European journal of health economics : HEPAC : health economics in prevention and care · 2020
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Chronic obstructive pulmonary disease (COPD) in Spain and the different aspects of its social impact: a multidisciplinary opinion document.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2020
    Article
  13. Article
  14. Trends in Hospitalization Expenditures for Acute Exacerbations of COPD in Beijing from 2009 to 2017.International journal of chronic obstructive pulmonary disease · 2020
    Article
  15. Impact of the financial crisis on COPD burden: Greece as a case study.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
  16. COPD uncovered: a cross-sectional study to assess the socioeconomic burden of COPD in Japan.International journal of chronic obstructive pulmonary disease · 2018
    Article
  17. The annual direct costs of stable COPD in Greece.International journal of chronic obstructive pulmonary disease · 2018
    Article
  18. Economic Burden of COPD by Disease Severity - A Nationwide Cohort Study in Denmark.International journal of chronic obstructive pulmonary disease
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kyriakos SouliotisDepartment of Social and Educational Policy, University of Peloponnese, Corinth.
Hara KousoulakouDepartment of Social and Educational Policy, University of Peloponnese, Corinth.
Georgios HillasDepartment of Pulmonary and Critical Care Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens.
Nikos TzanakisDepartment of Thoracic Medicine, Medical School, University General Hospital of Heraklion, Heraklion, Crete.
Michalis ToumbisSixth Pulmonary Department, "Sotiria" Hospital for Thoracic Diseases, Athens, Greece.
Theodoros VassilakopoulosDepartment of Pulmonary and Critical Care Medicine, Evangelismos Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCOPD is associated with significant economic burden. The objective of this study was to explore the direct and indirect costs associated with COPD and identify the key cost drivers of disease management in Greece.

methodsA Delphi panel of Greek pulmonologists was conducted, which aimed at eliciting local COPD treatment patterns and resource use. Resource use was translated into costs using official health insurance tariffs and Diagnosis-Related Groups (DRGs). In addition, absenteeism and caregiver's costs were recorded in order to quantify indirect COPD costs.

resultsThe total costs of managing COPD per patient per year were estimated at €4,730, with direct (medical and nonmedical) and indirect costs accounting for 62.5% and 37.5%, respectively. COPD exacerbations were responsible for 32% of total costs (€1,512). Key exacerbation-related cost drivers were hospitalization (€830) and intensive care unit (ICU) admission costs (€454), jointly accounting for 85% of total exacerbation costs. Annual maintenance phase costs were estimated at €835, with pharmaceutical treatment accounting for 77% (€639.9). Patient time costs were estimated at €146 per year. The average number of sick days per year was estimated at 16.9, resulting in productivity losses of €968. Caregiver's costs were estimated at €806 per year.

conclusionThe management of COPD in Greece is associated with intensive resource use and significant economic burden. Exacerbations and productivity losses are the key cost drivers. Cost containment policies should focus on prioritizing treatments that increase patient compliance as these can lead to reduction of exacerbations, longer maintenance phases, and thus lower costs.

Indexed as

Health Care CostsAbsenteeismCaregiversCost of IllnessDelphi TechniqueDisease ProgressionDrug CostsEfficiencyGreeceHealth ExpendituresHospital CostsHumansInsurance, HealthPractice Patterns, Physicians'Pulmonary Disease, Chronic ObstructivePulmonologistsburdenCOPDdirect costGreeceindirect cost

Identifiers

PMID28546747
PMCPMC5436756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.