SynthesisClinical interventions in aging2017
Effect of exercise on cognitive function in chronic disease patients: a meta-analysis and systematic review of randomized controlled trials.
Synthesis in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effect of exercise interventions on cognitive function in breast cancer patients and survivors: a systematic review with meta-analysis.Breast cancer (Tokyo, Japan) · 2025Pooled it
- Impact of exercise training on cognitive function in patients with COPD: a systematic review and meta-analysis of randomised controlled trials.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Pooled it
- The effect of mind-body exercise on memory in older adults: a systematic review and meta-analysis.Aging clinical and experimental research · 2021Pooled it
- Reversal of cognitive impairment in a hypotensive elderly population using a passive exercise intervention.Clinical interventions in aging · 2017Trial
- Examining the Effectiveness of Acceptance and Commitment Therapy on the Cognitive Functions of Patients with Systemic Lupus Erythematosus.Iranian journal of psychiatry · 2026Article
- Prevalence of Chronic Diseases by Cognitive Function Level and Age Group Among Middle-Aged and Older Korean Adults.International journal of geriatric psychiatry · 2025Article
- Article
- Harnessing Extended Reality for Neurocognitive Training in Chronic Pain: State of the Art, Opportunities, and Future Directions.Healthcare (Basel, Switzerland) · 2025Review
- Cognitive impairment in CKD patients: a guidance document by the CONNECT network.Clinical kidney journal · 2025Review
- Sedentary Lifestyle Is a Modifiable Risk Factor for Cognitive Impairment in Patients on Dialysis and after Kidney Transplantation.Journal of clinical medicine · 2024Article
- Unraveling of Molecular Mechanisms of Cognitive Frailty in Chronic Kidney Disease: How Exercise Makes a Difference.Journal of clinical medicine · 2024Review
- Soluble Klotho, a Potential Biomarker of Chronic Kidney Disease-Mineral Bone Disorders Involved in Healthy Ageing: Lights and Shadows.International journal of molecular sciences · 2024Review
- Association of health behaviors with function and health-related quality of life among patients with Parkinson's disease.Israel journal of health policy research · 2024Observational
- Physical exercise frequency and cognition: a multicenter cross-sectional cohort study.Frontiers in aging neuroscience · 2024Article
- Article
- Relationship Between Cognitive Performance, Physical Activity, and Socio-Demographic/Individual Characteristics Among Aging Americans.Journal of Alzheimer's disease : JAD · 2023Article
- Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-Neural plasticity · 2023Article
- Chronic kidney disease, physical activity and cognitive function in older adults-results from the National Health and Nutrition Examination Survey (2011-2014).Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022Article
- Cognitive impairment in heart failure: clinical implications, tools of assessment, and therapeutic considerations.Heart failure reviews · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to conduct a meta-analysis and systematic review to assess the effect of exercise on cognitive function in people with chronic diseases.
methodsPubMed, Web of Science, Embase, the Cochrane Library, CINAHL, PsycINFO, and three Chinese databases were electronically searched for papers that were published until September 2016. This meta-analysis and systematic review included randomized controlled trials that evaluated the effect of exercise on cognitive function compared with control group for people with chronic diseases.
resultsTotally, 35 studies met the inclusion criteria, with 3,113 participants. The main analysis revealed a positive overall random effect of exercise intervention on cognitive function in patients with chronic diseases. The secondary analysis revealed that aerobic exercise interventions and aerobic included exercise interventions had a positive effect on cognition in patients with chronic diseases. The intervention offering low frequency had a positive effect on cognitive function in patients with chronic diseases. Finally, we found that interventions offered at both low exercise intensity and moderate exercise intensity had a positive effect on cognitive function in patients with chronic diseases. The secondary analysis also revealed that exercise interventions were beneficial in Alzheimer's disease patients when grouped by disease type.
conclusionThis meta-analysis and systematic review suggests that exercise interventions positively influence cognitive function in patients with chronic diseases. Beneficial effect was independent of the type of disease, type of exercise, frequency, and the intensity of the exercise intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.