Evidence map›Paper›PMID 28546645›Full record

ArticleJournal of fluorine chemistry2016

Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias.

Thomas M Jeitner, Eva Kristoferson, Juan A Azcona, John T Pinto, Clint Stalnecker, Jon W Erickson, Hank F Kung, Jianyong Li, Karl Ploessl, Arthur J L Cooper

Abstract read
In one paragraph

Article in Journal of fluorine chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  2. Automated radiosynthesis of 5-[Nuclear medicine and biology · 2018
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Thomas M JeitnerDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
Eva KristofersonDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
Juan A AzconaDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
John T PintoDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
Clint StalneckerDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
Jon W EricksonDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.
Hank F KungDepartment of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Jianyong LiDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA.
Karl PloesslDepartment of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Arthur J L CooperDepartment of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
New York Medical College · USCornell University · USUniversity of Pennsylvania · USVirginia Tech · US

Funding

Novel PET imaging agents for understanding glutamine addiction in cancerR01CA164490 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CHODOSH, LEWIS A, KUNG, HANK F · 2011 to 2015
$4.0M
NCI NIH HHS R01 CA164490
6 · The paper itself

Abstract

Two 4-fluoro-L-glutamine diastereoisomers [(2

Indexed as

FluoroglutamateFluoroglutamineGlutamate-utilizing enzymesGlutamine-utilizing enzymes

Identifiers

PMID28546645
PMCPMC5440087
OpenAlexW2535431787

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.