SynthesisCancer research and treatment2018
Light Alcohol Drinking and Risk of Cancer: A Meta-Analysis of Cohort Studies.
Synthesis in Cancer research and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 5 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Pooled it
- The Combined Effects of Alcohol Consumption and Smoking on Cancer Risk by Exposure Level: A Systematic Review and Meta-Analysis.Journal of Korean medical science · 2024Pooled it
- Male- and female-specific reproductive risk factors across the lifespan for dementia or cognitive decline: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis.Epidemiology and health · 2023Pooled it
- Dietary Intake of Omega-3 fatty acids and Endocrine-related Gynecological Cancer: A Meta-Analysis of Observational Studies.Cancer research and treatment · 2019Pooled it
- Designing Effective Alcohol Warnings: Consumer Reactions to Icons and Health Topics.American journal of preventive medicine · 2023Trial
- Testing Alcohol Labels as a Tool to Communicate Cancer Risk to Drinkers: A Real-World Quasi-Experimental Study.Journal of studies on alcohol and drugs · 2020Trial
- Drinking Patterns, Sociodemographic Correlates and Sex Differences Among Ghanaians Aged 15-49 Years: A Cross-Sectional Study.Public health challenges · 2026Article
- Alcohol amount, drinking patterns, and gastric cancer risk: a nationwide study using targeted maximum likelihood estimation.European journal of epidemiology · 2026Article
- Trends and burden of colon and rectum cancer attributable to low physical activity in China: a comprehensive analysis from 1990 to 2021.Cancer causes & control : CCC · 2026Article
- Alcohol-attributable cancer risk and burden estimates for Australia's updated alcohol consumption guidelines.British journal of cancer · 2026Article
- Women's perceptions of breast cancer risk and prevention: insights into knowledge gaps and lifestyle attitudes.BMC public health · 2026Article
- Nomogram for predicting papillary thyroid carcinoma risk combined with clinical, biochemical and ultrasonographic indicators.BMC cancer · 2026Article
- Low Alanine Aminotransferase Levels in Alcohol Consuming Male Subjects, Carriers of the Common ALDH2 Deficient Variant, ALDH2*2.Hepatology research : the official journal of the Japan Society of Hepatology · 2025Review
- Response to Koker and Ozcelik.Journal of the National Cancer Institute · 2025Article
- Alcohol consumption and breast lesions: targets for risk-based screening in high-risk Italian women.Breast cancer (Tokyo, Japan) · 2025Article
- Association of lifestyle factors with breast cancer incidence: An overview of systematic reviews.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2025Article
- Exploring the anticancer potential of nitrated N-substituted-4-hydroxy-2-quinolone-3-carboxamides: synthesis, biological assessment, and computational analysis.BMC chemistry · 2025Article
- Reported prevalence and risk factors of malignant tumors in the elderly population in China: a nationwide cross-sectional study.Aging clinical and experimental research · 2025Article
- A longitudinal analysis on alcohol consumption in patients with cancer undergoing psycho-oncological treatment.Scientific reports · 2025Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to determine whether light alcohol drinking increases the risk of cancer by using a meta-analysis of cohort studies because the newly revised 2015 European Code against Cancer fourth edition on alcohol and cancer was based on critical flaws in the interpretation and citation of the previous meta-analyses. MATERIALS AND
methodsPubMed and EMBASE were searched in April, 2016. Two authors independently reviewed and selected cohort studies on the association between very light (≤ 0.5 drink/day), light (≤ 1 drink/day), or moderate drinking (1-2 drinks/day) and the risk of cancer incidence and mortality. A pooled relative riskwith its 95% confidence intervalwas calculated by a random-effects meta-analysis. Main outcome measures were cancer incidence and mortality.
resultsA total of 60 cohort studies from 135 articles were included in the final analysis. Very light drinking or light drinking was not associated with the incidence of most cancers except for female breast cancer in women and male colorectal cancer. Conversely, light drinking was associated with a decreased incidence of both female and male lung cancer significantly and both female and male thyroid cancer marginally significantly. Moderate drinking significantly increased the incidence of male colorectal cancer and female breast cancer,whereas it decreased the incidence of both female and male hematologic malignancy.
conclusionWe found that very light or light alcohol drinking was not associated with the risk of most of the common cancers except for the mild increase in the incidence of breast cancer in women and colorectal cancer in men.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.