ReviewCirculation research2017
Gut Microbiota: Potential for a Unifying Hypothesis for Prevention and Treatment of Hypertension.
Abstract readReview
In one paragraph
Review in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gut microbiota changes in patients with hypertension: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2023Pooled it
- Gut Microbiota Dysbiosis in Human Hypertension: A Systematic Review of Observational Studies.Frontiers in cardiovascular medicine · 2021Pooled it
- Trial
- High-fat diet increases circulating palmitic acid produced by gut Bacteroides thetaiotaomicron to promote thrombosis.Cell reports. Medicine · 2025Article
- Effects of gut microbiota dysbiosis on the metabolism and pharmacokinetics of losartan in rats: from endogenous to ceftriaxone-induced dysbiosis.Frontiers in microbiology · 2025Article
- Alterations of gut microbiota are associated with blood pressure: a cross-sectional clinical trial in Northwestern China.Journal of translational medicine · 2023Article
- Exploring a novel therapeutic strategy: the interplay between gut microbiota and high-fat diet in the pathogenesis of metabolic disorders.Frontiers in nutrition · 2023Review
- The role of short-chain fatty acids produced by gut microbiota in the regulation of pre-eclampsia onset.Frontiers in cellular and infection microbiology · 2023Review
- Review
- Assessing the impact of blood pressure in the development of inflammatory bowel disease.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Tumor Necrosis Factor Alpha and the Gastrointestinal Epithelium: Implications for the Gut-Brain Axis and Hypertension.Cellular and molecular neurobiology · 2022Review
- Intestinal microbiota: A promising therapeutic target for hypertension.Frontiers in cardiovascular medicine · 2022Review
- Interactions amongst inflammation, renin-angiotensin-aldosterone and kallikrein-kinin systems: suggestive approaches for COVID-19 therapy.The journal of venomous animals and toxins including tropical diseases · 2021Review
- ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.Hypertension (Dallas, Tex. : 1979) · 2020Review
- Diurnal Timing Dependent Alterations in Gut Microbial Composition Are Synchronously Linked to Salt-Sensitive Hypertension and Renal Damage.Hypertension (Dallas, Tex. : 1979) · 2020Article
- Metabolites and Hypertension: Insights into Hypertension as a Metabolic Disorder: 2019 Harriet Dustan Award.Hypertension (Dallas, Tex. : 1979) · 2020Review
- Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2.Circulation research · 2020Review
- Potential benefits of garlic and other dietary supplements for the management of hypertension.Experimental and therapeutic medicine · 2020Review
- Linking gut microbiota with the human diseases.Bioinformation · 2020Article
- Electroacupuncture Inhibits Atherosclerosis through Regulating Intestinal Flora and Host Metabolites in Rabbit.Evidence-based complementary and alternative medicine : eCAM · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
YanFei QiFrom the Division of Cardiovascular Medicine, Department of Medicine (Y.Q., C.J.P.) and Department of Physiology and Functional Genomics (S.K., E.M.R., M.K.R.), College of Medicine, University of Florida, Gainesville.
Seungbum KimFrom the Division of Cardiovascular Medicine, Department of Medicine (Y.Q., C.J.P.) and Department of Physiology and Functional Genomics (S.K., E.M.R., M.K.R.), College of Medicine, University of Florida, Gainesville.
Elaine M RichardsFrom the Division of Cardiovascular Medicine, Department of Medicine (Y.Q., C.J.P.) and Department of Physiology and Functional Genomics (S.K., E.M.R., M.K.R.), College of Medicine, University of Florida, Gainesville.
Mohan K RaizadaFrom the Division of Cardiovascular Medicine, Department of Medicine (Y.Q., C.J.P.) and Department of Physiology and Functional Genomics (S.K., E.M.R., M.K.R.), College of Medicine, University of Florida, Gainesville.
Carl J PepineFrom the Division of Cardiovascular Medicine, Department of Medicine (Y.Q., C.J.P.) and Department of Physiology and Functional Genomics (S.K., E.M.R., M.K.R.), College of Medicine, University of Florida, Gainesville. carl.pepine@medicine.ufl.edu mraizada@ufl.edu.
Funding
Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2MCVD protection mechanisms involving ACE2/Ang-(1-7) axisR01HL056921 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 1996 to 2015
$9.2MBrain Angiotensin In Hypertensive Neurons in CultureR37HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2003 to 2012
$5.8MUFRCC for Cardiovascular Cell Therapy Research NetworkUM1HL087366 · NHLBI · UNIVERSITY OF FLORIDA · PI PEPINE, CARL J · 2012 to 2018
$4.7MBrain-Gut Microbiome-Immune Axis in HypertensionR01HL132448 · NHLBI · UNIVERSITY OF FLORIDA · PI Carl J Pepine, Steven Michael Smith · 2016 to 2026
$4.5MBRAIN ANGIOTENSIN IN HYPERTENSIVE NEURONS IN CULTURER01HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K., SUMNERS, COLIN · 1985 to 2017
$4.3MAngiotensin-Converting Enzyme2 in Vascular Endothelial FunctionR01HL102033 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2010 to 2019
$4.3MNCATS NIH HHS UL1 TR001427NHLBI NIH HHS R01 HL033610NHLBI NIH HHS R01 HL056921NHLBI NIH HHS R01 HL102033NHLBI NIH HHS R01 HL132448NHLBI NIH HHS R37 HL033610NHLBI NIH HHS UM1 HL087366
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsAntihypertensive AgentsGastrointestinal MicrobiomeHumansHypertensionProbioticsTreatment OutcomeAntihypertensive Agentsbiomarkerdysbiosisgut microbiotaresistant hypertensiontreatment
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.