Evidence map›Paper›PMID 28546289›Full record

ArticleDisease models & mechanisms2017

A tripeptidyl peptidase 1 is a binding partner of the Golgi pH regulator (GPHR) in

Maria Stumpf, Rolf Müller, Berthold Gaßen, Regina Wehrstedt, Petra Fey, Malte A Karow, Ludwig Eichinger, Gernot Glöckner, Angelika A Noegel

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Assaying Lysosomal Enzyme Activity in Dictyostelium discoideum.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  2. Cells · 2022
    Review
  3. An altered transcriptome underliesFrontiers in genetics · 2022
    Article
  4. Development ofFrontiers in microbiology · 2022
    Article
  5. Mfsd8 Modulates Growth and the Early Stages of Multicellular Development inFrontiers in cell and developmental biology · 2022
    Article
  6. Autophagy in the Neuronal Ceroid Lipofuscinoses (Batten Disease).Frontiers in cell and developmental biology · 2022
    Review
  7. Repurposing proteases: AnBioresource technology reports · 2021
    Article
  8. Characterization of ZmCOLD1, novel GPCR-Type G Protein genes involved in cold stress fromPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021
    Article
  9. Aberrant Autophagy Impacts Growth and Multicellular Development in aFrontiers in cell and developmental biology · 2021
    Article
  10. Cellular models of Batten disease.Biochimica et biophysica acta. Molecular basis of disease · 2020
    Review
  11. Review
  12. Changing Times for CLN2 Disease: The Era of Enzyme Replacement Therapy.Therapeutics and clinical risk management · 2020
    Review
  13. Article
  14. Actin Waves and Dynamic Patterning of the Plasma Membrane.The Yale journal of biology and medicine · 2019
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Maria StumpfInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Rolf MüllerInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Berthold GaßenInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Regina WehrstedtInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Petra FeyDicty Base, Northwestern University, Biomedical Informatics Center and Center for Genetic Medicine, Chicago, IL 60611, USA.
Malte A KarowInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Ludwig EichingerInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany noegel@uni-koeln.de ludwig.eichinger@uni-koeln.de.
Gernot GlöcknerInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany.
Angelika A NoegelInstitute of Biochemistry I, Medical Faculty, University Hospital Cologne, Center for Molecular Medicine Cologne, University of Cologne, Joseph-Stelzmann-Str. 52, Köln 50931, Germany noegel@uni-koeln.de ludwig.eichinger@uni-koeln.de.ORCID 0000-0001-8260-6732
University of Cologne · DENorthwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in tripeptidyl peptidase 1 (

Indexed as

Amino Acid SequenceAminopeptidasesDictyosteliumDipeptidyl-Peptidases and Tripeptidyl-PeptidasesGene Knockout TechniquesGolgi ApparatusGreen Fluorescent ProteinsHydrogen-Ion ConcentrationPhenotypeProtein BindingProtein TransportProtozoan ProteinsSerine ProteasesSubcellular FractionsTripeptidyl-Peptidase 1AminopeptidasesDipeptidyl-Peptidases and Tripeptidyl-PeptidasesGreen Fluorescent ProteinsProtozoan ProteinsSerine ProteasesTripeptidyl-Peptidase 1EndosomesGolgi pH regulator (GPHR)LysosomesNeuronal ceroid lipofuscinosis (NCL)Tripeptidyl peptidase 1 (TPP1)

Identifiers

PMID28546289
PMCPMC5536908
OpenAlexW2619580074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.