Evidence map›Paper›PMID 28546222›Full record

ArticleDiabetes care2017

Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents.

Maria E Craig, Nicole Prinz, Claire T Boyle, Fiona M Campbell, Timothy W Jones, Sabine E Hofer, Jill H Simmons, Naomi Holman, Elaine Tham, Elke Fröhlich-Reiterer and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 143 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Continuous glucose monitoring evidence of celiac disease in type 1 diabetes.Journal of pediatric endocrinology & metabolism : JPEM · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Coeliac disease: complications and comorbidities.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  14. Review
  15. Article
  16. Observational
  17. Article
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 5 countries.

Maria E CraigThe Children's Hospital at Westmead, Sydney, New South Wales, Australia m.craig@unsw.edu.au.ORCID 0000-0001-6004-576X
Nicole PrinzInstitute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany.
Claire T BoyleJaeb Center for Health Research, Tampa, FL.
Fiona M CampbellLeeds Children's Hospital, Leeds, U.K.
Timothy W JonesThe University of Western Australia, Perth, Western Australia, Australia.
Sabine E HoferDepartment of Pediatrics, Medical University of Innsbruck, Innsbruck, Austria.
Jill H SimmonsVanderbilt University Medical Center, Nashville, TN.
Naomi HolmanInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, U.K.
Elaine ThamWomen's and Children's Hospital, Adelaide, South Australia, Australia.
Elke Fröhlich-ReitererDepartment of Pediatrics, Medical University of Graz, Graz, Austria.
Stephanie DuBoseJaeb Center for Health Research, Tampa, FL.
Helen ThorntonSt. Helens and Knowsley Teaching Hospitals NHS Trust, St. Helens, U.K.
Bruce KingJohn Hunter Children's Hospital, Hunter Medical Research Institute, University of Newcastle, Callaghan, New South Wales, Australia.
David M MaahsLucile Salter Packard Children's Hospital Stanford, Stanford University Medical Center, Palo Alto, CA.
Reinhard W HollInstitute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany.
Justin T WarnerChildren's Hospital for Wales, Cardiff, U.K.
Australasian Diabetes Data Network (ADDN)
T1D Exchange Clinic Network (T1DX)
National Paediatric Diabetes Audit (NPDA) and the Royal College of Paediatrics and Child Health
Prospective Diabetes Follow-up Registry (DPV) initiative
Jaeb Center for Health Research · USUniversität Ulm · DEHunter Medical Research Institute · AUInnsbruck Medical University · ATLeeds Teaching Hospitals NHS Trust · GBLucile Packard Children's Hospital · USMedical University of Graz · ATNoah's Ark Children's Hospital for Wales · GBSt Helens and Knowsley Teaching Hospitals NHS Trust · GBThe Kids Research Institute Australia · AUThe University of Sydney · AUUniversity of Glasgow · GBVanderbilt University Medical Center · USWomen's and Children's Hospital · AU

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
Training Grant in Pediatric Endocrinology, Diabetes and MetabolismT32DK065522 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHARON E. OBERFIELD · 2005 to 2026
$4.6M
NIDDK NIH HHS T32 DK065522
6 · The paper itself

Abstract

objectiveCeliac disease (CD) has a recognized association with type 1 diabetes. We examined international differences in CD prevalence and clinical characteristics of youth with coexisting type 1 diabetes and CD versus type 1 diabetes only. RESEARCH DESIGN AND

methodsData sources were as follows: the Prospective Diabetes Follow-up Registry (DPV) (Germany/Austria); the T1D Exchange Clinic Network (T1DX) (U.S.); the National Paediatric Diabetes Audit (NPDA) (U.K. [England/Wales]); and the Australasian Diabetes Data Network (ADDN) (Australia). The analysis included 52,721 youths <18 years of age with a clinic visit between April 2013 and March 2014. Multivariable linear and logistic regression models were constructed to analyze the relationship between outcomes (HbA

resultsBiopsy-confirmed CD was present in 1,835 youths (3.5%) and was diagnosed at a median age of 8.1 years (interquartile range 5.3-11.2 years). Diabetes duration at CD diagnosis was <1 year in 37% of youths, >1-2 years in 18% of youths, >3-5 years in 23% of youths, and >5 years in 17% of youths. CD prevalence ranged from 1.9% in the T1DX to 7.7% in the ADDN and was higher in girls than boys (4.3% vs. 2.7%,

conclusionsCD is a common comorbidity in youth with type 1 diabetes. Differences in CD prevalence may reflect international variation in screening and diagnostic practices, and/or CD risk. Although glycemic control was not different, the lower height SDS supports close monitoring of growth and nutrition in this population.

Indexed as

RegistriesAdolescentAustraliaBlood GlucoseCeliac DiseaseChildChild, PreschoolComorbidityDiabetes Mellitus, Type 1EnglandFemaleFollow-Up StudiesGermanyGlycated HemoglobinHumansMaleBlood GlucoseGlycated Hemoglobin

Identifiers

PMID28546222
PMCPMC6463736
OpenAlexW2617859352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.