Evidence map›Paper›PMID 28545981›Full record

ReviewVision research2017

The role of dyslipidemia in diabetic retinopathy.

Sandra S Hammer, Julia V Busik

Open access · greenAbstract readReview
In one paragraph

Review in Vision research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Potential Effects of Sweet Potato (International journal of molecular sciences · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sandra S HammerDepartment of Physiology, Michigan State University, East Lansing, MI, United States.
Julia V BusikDepartment of Physiology, Michigan State University, East Lansing, MI, United States. Electronic address: busik@msu.edu.
Michigan State University · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Dyslipidemia and Diabetic RetinopathyR01EY016077 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI BUSIK, JULIA V · 2005 to 2025
$6.3M
LXR as a Novel Therapeutic Target in Diabetic RetinopathyR01EY025383 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BUSIK, JULIA V, GRANT, MARIA BARTOLOMEO · 2015 to 2024
$4.2M
NEI NIH HHS R01 EY016077NEI NIH HHS R01 EY025383NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

Diabetic retinopathy (DR) affects over 93million people worldwide and is the number one cause of blindness among working age adults. These indicators coupled with the projected rise of patients diagnosed with diabetes, makes DR a serious and prevalent vision threating disease. Data from recent clinical trials demonstrate that in addition to the well accepted role of hyperglycemia, dyslipidemia is an important, but often overlooked factor in the development of DR. The central aim of this review article is to showcase the critical role of dyslipidemia in DR progression as well as highlight novel therapeutic solutions that take advantage of the vital roles lipid metabolism plays in DR progression.

Indexed as

Diabetic RetinopathyDisease ProgressionDyslipidemiasHumansLipid MetabolismASMBone marrowCholesterol metabolismDiabetic retinopathyDyslipidemiaFatty acidsInflammationLiver X receptormiR-15a

Identifiers

PMID28545981
PMCPMC5702582
OpenAlexW2619215897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.