Evidence map›Paper›PMID 28545795›Full record

ArticleJournal of psychosomatic research2017

Fear and distress disorders as predictors of heart disease: A temporal perspective.

A M Roest, P de Jonge, C W W Lim, D J Stein, A Al-Hamzawi, J Alonso, C Benjet, R Bruffaerts, B Bunting, J M Caldas-de-Almeida and 12 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychosomatic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 20 institutions in 18 countries.

A M RoestUniversity of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), Groningen, The Netherlands. Electronic address: a.m.roest@umcg.nl.
P de JongeUniversity of Groningen, University Medical Center Groningen, Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), Groningen, The Netherlands; University of Groningen, Department of Psychology, Developmental Psychology, Groningen, the Netherlands.
C W W LimDepartment of Psychological Medicine, University of Otago, Dunedin, New Zealand; Queensland Brain Institute, University of Queensland, St Lucia and Queensland Centre for Mental Health Research, Wacol, Queensland, Australia.
D J SteinDepartment of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
A Al-HamzawiCollege of Medicine, Al-Qadisiya University, Diwania Governorate, Iraq.
J AlonsoIMIM-Hospital del Mar Research Institute, Parc de Salut Mar; Pompeu Fabra University (UPF); and CIBER en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
C BenjetDepartment of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramón de la Fuente, Mexico City, Mexico.
R BruffaertsPsychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg Leuven, Belgium.
B BuntingPsychology Research Institute, Ulster University, Northern Ireland, United Kingdom.
J M Caldas-de-AlmeidaChronic Diseases Research Center (CEDOC) and Department of Mental Health, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
M CiutanNational School of Public Health, Management and Professional Development, Bucharest, Romania.
G de GirolamoIRCCS St John of God Clinical Research Centre, IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy.
C HuShenzhen Insitute of Mental Health & Shenzhen Kanging Hospital, Shenzhen, China.
D LevinsonMinistry of Health Israel, Mental Health Services, Israel.
Y NakamuraDepartment of Public Health, Jichi Medical University, Shimotsuke, Tochigi, Japan.
F Navarro-MateuIMIB-Arrixaca, CIBERESP-Murcia, Subdirección General de Salud Mental y Asistencia Psiquiátrica, Servicio Murciano de Salud, El Palmar (Murcia), Spain.
M PiazzaNational Institute of Health, Peru, Universidad Cayetano Hereidia, Peru.
J Posada-VillaColegio Mayor de Cundinamarca University, Bogota, Colombia.
Y TorresCenter for Excellence on Research in Mental Health, CES University, Medellin, Colombia.
B WojtyniakCentre of Monitoring and Analyses of Population Health, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
R C KesslerDepartment of Health Care Policy, Harvard University Medical School, Boston, MA, United States.
K M ScottDepartment of Psychological Medicine, University of Otago, Dunedin, New Zealand.
University Medical Center Groningen · NLCentro San Giovanni di Dio Fatebenefratelli · ITHarvard University · USInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXIsrael Ministry of Health · ILJichi Medical University · JPNarodowy Instytut Zdrowia Publicznego PZH – Państwowy Instytut Badawczy · PLNational School of Public Health, Management and Professional Development · ROServicio Murciano de Salud · ESShenzhen KangNing Hospital · CNThe University of Queensland · AUUniversidad CES · COUniversidad Colegio Mayor de Cundinamarca · COUniversidade Nova de Lisboa · PTUniversitair Ziekenhuis Leuven · BEUniversitat Pompeu Fabra · ESUniversity of Al-Qadisiyah · IQUniversity of Cape Town · ZAUniversity of Otago · NZUniversity of Ulster · GB

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS K05 DA015799NIDA NIH HHS R01 DA016558NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220
6 · The paper itself

Abstract

objectiveFew studies have been able to contrast associations of anxiety and depression with heart disease. These disorders can be grouped in fear and distress disorders. Aim of this study was to study the association between fear and distress disorders with subsequent heart disease, taking into account the temporal order of disorders.

methodsTwenty household surveys were conducted in 18 countries (n=53791; person years=2,212,430). The Composite International Diagnostic Interview assessed lifetime prevalence and age at onset of disorders, and respondents were categorized into categories based on the presence and timing of fear and distress disorders. Heart disease was indicated by self-report of physician-diagnosed heart disease or self-report of heart attack, together with year of onset. Survival analyses estimated associations between disorder categories and heart disease.

resultsMost respondents with fear or distress disorders had either pure distress or pure fear (8.5% and 7.7% of total sample), while fear preceded distress in the large majority of respondents with comorbid fear and distress (3.8% of total sample). Compared to the "no fear or distress disorder" category, respondents with pure fear disorder had the highest odds of subsequent heart disease (OR:1.8; 95%CI:1.5-2.2; p<0.001) and compared to respondents with pure distress disorder, these respondents were at a significantly increased risk of heart disease (OR:1.3; 95%CI:1.0-1.6; p=0.020).

conclusionThis novel analytic approach indicates that the risk of subsequent self-reported heart disease associated with pure fear disorder is significantly larger than the risk associated with distress disorder. These results should be confirmed in prospective studies using objective measures of heart disease.

Indexed as

FearAdultAnxiety DisordersDepressive DisorderHeart DiseasesHumansPrevalenceRiskSelf ReportTime FactorsAnxietyClassificationDepressionDistressFearHeart disease

Identifiers

PMID28545795
PMCPMC5674522
OpenAlexW2601511582

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.