Evidence map›Paper›PMID 28545724›Full record

ReviewCell calcium2018

The role of Ca

Pamela Maher, Klaus van Leyen, Partha Narayan Dey, Birgit Honrath, Amalia Dolga, Axel Methner

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell calcium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 211 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Ferroptosis in plant immunity.Plant communications · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Pamela MaherCellular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.
Klaus van LeyenHarvard Medical School, Cambridge, MA, USA.
Partha Narayan DeyUniversity Medical Center and Focus Program Translational Neuroscience (FTN) of the Johannes Gutenberg University Mainz, Department of Neurology, Mainz, Germany.
Birgit HonrathDepartment of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.
Amalia DolgaDepartment of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.
Axel MethnerUniversity Medical Center and Focus Program Translational Neuroscience (FTN) of the Johannes Gutenberg University Mainz, Department of Neurology, Mainz, Germany. Electronic address: axel.methner@gmail.com.
Johannes Gutenberg University Mainz · DEUniversity of Groningen · NLHarvard University · USSalk Institute for Biological Studies · US

Funding

12-Lipoxygenase and Ischemic Brain Cell DeathR01NS049430 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI VAN LEYEN, KLAUS · 2005 to 2015
$3.6M
Modulation of the Innate Immune Response by Fisetin Derivatives for the Treatment of ADR42AI104034 · NIAID · VIROGENICS, INC. · PI MAHER, PAMELA ANNE · 2016 to 2017
$1.5M
Modulation of the Innate Immune System by Fisetin for the Treatment of ADR41AI104034 · NIAID · VIROGENICS, INC. · PI MAHER, PAMELA ANNE · 2013 to 2014
$600k
Novel 12/15 lipoxygenase inhibitors for the treatment of strokeR21NS087165 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI VAN LEYEN, KLAUS · 2014 to 2015
$576k
NIAID NIH HHS R41 AI104034NIAID NIH HHS R42 AI104034NINDS NIH HHS R01 NS049430NINDS NIH HHS R21 NS087165
6 · The paper itself

Abstract

Ca

Indexed as

ApoptosisAnimalsCalciumGlutamic AcidHumansIronMitochondriaOxidative StressCalciumGlutamic AcidIronCalciumFerroptosisOxidative stressOxytosisSOCE

Identifiers

PMID28545724
PMCPMC5682235
OpenAlexW2612801017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.