ArticleBMC biotechnology2017
Pigment fingerprint profile during extractive fermentation with Monascus anka GIM 3.592.
Article in BMC biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Integrative Metabolomic and Transcriptomic Analyses Uncover Metabolic Alterations and Pigment Diversity inmSystems · 2021Article
- Measurement Techniques to Resolve and Control Population Dynamics of Mixed-Culture Processes.Trends in biotechnology · 2021Review
- Safety Evaluation of Fungal Pigments for Food Applications.Journal of fungi (Basel, Switzerland) · 2021Review
- Metabolites from halophilic bacterial isolates3 Biotech · 2021Article
- Tracking of pigment accumulation and secretion in extractive fermentation of Monascus anka GIM 3.592.Microbial cell factories · 2017Article
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Authors and funding
5 authors.
Funding
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Abstract
backgroundTraditional submerged fermentation mainly accumulates intracellular orange pigments with absorption maxima at 470 nm, whereas extractive fermentation of Monascus spp. with Triton X-100 can promote the export of intracellular pigments to extracellular broth, mainly obtaining extracellular yellow pigments with absorption maxima at approximately 410 nm. In this study, a strain of Monascus (M. anka GIM 3.592) that produces high yields of pigments was employed to investigate the differences in pigment fingerprint profiles between submerged and extractive fermentations.
resultsUsing extractive fermentation with this high-yield strain, the extracellular pigments exhibited an absorption maximum at 430 nm, not 410 nm, as previously observed. By comparing the pigment fingerprint profiles between submerged and extractive fermentations, extractive fermentation was found to not only export intracellular pigments to the extracellular broth, but also to form four other yellow pigments (Y1-Y4) that accounted for a large proportion of the extracellular pigments and that were not produced in submerged fermentation. The yields of Y1-Y4 were closely related to the concentration and feeding time point of Triton X-100. Y1-Y4 presented identical UV-Vis spectra with absorption maxima at 430 nm and fluorescence spectra with absorption maxima (emission) at 565 nm. HPLC-MS and the spectral analysis showed that the four pigments (Y1-Y4) had not been previously reported. The results indicated that these pigments may rely on the bioconversion of orange pigments (rubropunctatin and monascorubrin).
conclusionsUsing extractive fermentation with M. anka led to a high yield of extracellular yellow pigments (AU
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