Evidence map›Paper›PMID 28545530›Full record

ArticleBMC surgery2017

Hypomagnesemia predicts postoperative biochemical hypocalcemia after thyroidectomy.

Han Luo, Hongliu Yang, Wanjun Zhao, Tao Wei, Anping Su, Bin Wang, Jingqiang Zhu

Abstract read
In one paragraph

Article in BMC surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Effect of Histamine-2 Receptor Antagonists on Hypocalcemia after Thyroidectomy: A Retrospective Cohort Study and Sensitivity Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  5. Rapid method for screening of both calcium and magnesium chelation with comparison of 21 known metal chelators.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  6. Article
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  9. Article
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  12. Association of Hypomagnesemia with Hypocalcemia after Thyroidectomy.Indian journal of endocrinology and metabolism
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Han LuoDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China.
Hongliu YangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, People's Republic of China.
Wanjun ZhaoDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China.
Tao WeiDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China.
Anping SuDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China.
Bin WangDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China.
Jingqiang ZhuDepartment of Thyroid & Parathyroid surgery, West China Hospital, Sichuan University, Guoxue Alley 37#, Chengdu, Sichuan, 610041, People's Republic of China. zjq-wkys@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the role of magnesium in biochemical and symptomatic hypocalcemia, a retrospective study was conducted.

methodsLess-than-total thyroidectomy patients were excluded from the final analysis. Identified the risk factors of biochemical and symptomatic hypocalcemia, and investigated the correlation by logistic regression and correlation test respectively.

resultsA total of 304 patients were included in the final analysis. General incidence of hypomagnesemia was 23.36%. Logistic regression showed that gender (female) (OR = 2.238, p = 0.015) and postoperative hypomagnesemia (OR = 2.010, p = 0.017) were independent risk factors for biochemical hypocalcemia. Both Pearson and partial correlation tests indicated there was indeed significant relation between calcium and magnesium. However, relative decreasing of iPTH (>70%) (6.691, p < 0.001) and hypocalcemia (2.222, p = 0.046) were identified as risk factors of symptomatic hypocalcemia. The difference remained significant even in normoparathyroidism patients.

conclusionsPostoperative hypomagnesemia was independent risk factor of biochemical hypocalcemia. Relative decline of iPTH was predominating in predicting symptomatic hypocalcemia.

Indexed as

AdultCalciumFemaleHumansHypocalcemiaIncidenceMagnesiumMaleMiddle AgedPostoperative ComplicationsPostoperative PeriodRetrospective StudiesRisk FactorsThyroidectomyCalciumMagnesiumFemaleHypocalcemiaHypomagnesemiaRelative decline of iPTHSymptom

Identifiers

PMID28545530
PMCPMC5445405

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.