Evidence map›Paper›PMID 28545476›Full record

ArticleBMC infectious diseases2017

Prenatal diagnosis and prevention of toxoplasmosis in pregnant women in Northern Vietnam: study protocol.

G Suzanne A Smit, Thi Lam Binh Vu, Trung Dung Do, Niko Speybroeck, Brecht Devleesschauwer, Elizaveta Padalko, Ellen Roets, Pierre Dorny

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Seroprevalence ofIranian journal of parasitology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

G Suzanne A SmitDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium. suzanne.smit@ugent.be.ORCID 0000-0002-8254-7688
Thi Lam Binh VuParasitology Department of the National Institute of Malariology, Parasitology and Entomology (NIMPE), 245 Luong The Vinh, Nam Tu Liem, Ha Noi, Viet Nam.
Trung Dung DoParasitology Department of the National Institute of Malariology, Parasitology and Entomology (NIMPE), 245 Luong The Vinh, Nam Tu Liem, Ha Noi, Viet Nam.
Niko SpeybroeckInstitute of Health and Society (IRSS), Université catholique de Louvain, Clos Chapelle-aux-champs 30, 1200 Woluwe-Saint Lambert, Brussels, Belgium.
Brecht DevleesschauwerDepartment of Public Health and Surveillance, Scientific Institute of Public Health (WIV-ISP), Juliette Wytsmanstraat 14, 1050, Brussels, Belgium.
Elizaveta PadalkoDepartment of Clinical Biology, Microbiology and Immunology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Ellen RoetsWomen's Clinic, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Pierre DornyDepartment of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
Ghent University · BEGhent University Hospital · BENational Institute of Malariology, Parasitology and Entomology · VNInstitut Scientifique de Santé Publique · BEUCLouvain · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Vietnam, no systematic prenatal toxoplasmosis screening is in place, and only few studies have assessed the prevalence and importance of this zoonotic parasite infection. In addition, no studies have been conducted to assess the risk factors associated with toxoplasmosis. This study protocol was developed to determine the seroprevalence of toxoplasmosis in pregnant women in Hanoi and Thai Binh, Northern Vietnam, and to evaluate the association with risk factors and congenital toxoplasmosis. The protocol was developed in a way that it could potentially evolve into a countrywide prenatal diagnosis and prevention program, with the main focus on primary prevention.

methodsThe collaborating gynaecologists will invite eligible pregnant women attending antenatal care for the first time to participate in the study. At first consult, information about toxoplasmosis and its prevention will be provided. All participants will be asked to fill in a questionnaire, which is designed to analyse socio-demographic and biologically plausible risk factors associated with toxoplasmosis, and blood samples will be collected to determine the seroprevalence of toxoplasmosis in pregnant women. In case there is suspicion of a primary infection during pregnancy, the concerned women will be followed-up by the gynaecologists according to a predefined protocol. Every participant will be informed on her serological status, risk factors and prevention measures and is offered appropriate medical information and medical follow-up if required. DISCUSSION: The hypothesis is that congenital toxoplasmosis is an important but currently under-diagnosed public health problem in Vietnam. This study can strengthen sustainable control of toxoplasmosis in Vietnam, provide a protocol for prenatal diagnosis, boost overall awareness, improve the knowledge about toxoplasmosis prevention and can be essential for evidence-based health policy.

Indexed as

AdolescentAdultFemaleHumansPregnancyPregnancy Complications, ParasiticPrenatal CarePrenatal DiagnosisPublic HealthRisk FactorsSeroepidemiologic StudiesSurveys and QuestionnairesToxoplasmosisToxoplasmosis, CongenitalVietnamYoung AdultCongenital toxoplasmosisPrenatal diagnosticsPreventionSerologyToxoplasmosis during pregnancyVietnam

Identifiers

PMID28545476
PMCPMC5445302
OpenAlexW2618061870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.