ArticleBMC evolutionary biology2017
The impact of migratory flyways on the spread of avian influenza virus in North America.
Article in BMC evolutionary biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Rapid Expansion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Genotype D1.1 Virus across Flyway Regions, North America, Fall 2024.Emerging infectious diseases · 2026Article
- Assessing HPAI-H5 transmission risk across wild bird migratory flyways in the United States.Nature communications · 2026Article
- Transboundary Spread and Ecological Drivers of HPAI H5N1 Clade 2.3.4.4b During the 2022-2023 Outbreak in Chile: An Integrated Genomic and Spatial Epidemiology Framework.Transboundary and emerging diseases · 2026Article
- Intensive transmission in wild, migratory birds drove rapid geographic dissemination and repeated spillovers of H5N1 into agriculture in North America.bioRxiv : the preprint server for biology · 2025Article
- The emergence of highly pathogenic avian influenza H5N1 in dairy cattle: implications for public health, animal health, and pandemic preparedness.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Review
- Using homologous network to identify reassortment risk in H5Nx avian influenza viruses.PLoS computational biology · 2025Article
- Emergence, migration and spreading of the high pathogenicity avian influenza virus H5NX of the Gs/Gd lineage into America.The Journal of general virology · 2025Review
- The evolution and epidemiology of H3N2 canine influenza virus after 20 years in dogs.Epidemiology and infection · 2025Article
- Improvements in RNA and DNA nanopore sequencing allow for rapid genetic characterization of avian influenza.Virus evolution · 2025Article
- Article
- Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle.Emerging microbes & infections · 2024Article
- Genotypic Clustering of H5N1 Avian Influenza Viruses in North America Evaluated by Ordination Analysis.Viruses · 2024Article
- Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024.Emerging infectious diseases · 2024Article
- Using an adaptive modeling framework to identify avian influenza spillover risk at the wild-domestic interface.Scientific reports · 2024Article
- Tracing the Flight: Investigating the Introduction of Avian Metapneumovirus (aMPV) A and B.Animals : an open access journal from MDPI · 2024Article
- Descriptive Epidemiology and Phylodynamics of the "First Wave" of an Outbreak of Highly Pathogenic Avian Influenza (H5N1 Clade 2.3.4.4b) in British Columbia and the Yukon, Canada, April to September 2022.Transboundary and emerging diseases · 2024Article
- Baseline health parameters of rhinoceros auklets (Frontiers in veterinary science · 2024Article
- Novel Epidemiologic Features of High Pathogenicity Avian Influenza Virus A H5N1 2.3.3.4b Panzootic: A Review.Transboundary and emerging diseases · 2024Review
- Nanopore MinION Sequencing Generates a White Spot Syndrome Virus Genome from a Pooled Cloacal Swab Sample of Domestic Chickens in South Africa.Microorganisms · 2023Article
- Can Citizen Science Contribute to Avian Influenza Surveillance?Pathogens (Basel, Switzerland) · 2023Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWild birds are the major reservoir hosts for influenza A viruses (AIVs) and have been implicated in the emergence of pandemic events in livestock and human populations. Understanding how AIVs spread within and across continents is therefore critical to the development of successful strategies to manage and reduce the impact of influenza outbreaks. In North America many bird species undergo seasonal migratory movements along a North-South axis, thereby providing opportunities for viruses to spread over long distances. However, the role played by such avian flyways in shaping the genetic structure of AIV populations remains uncertain.
resultsTo assess the relative contribution of bird migration along flyways to the genetic structure of AIV we performed a large-scale phylogeographic study of viruses sampled in the USA and Canada, involving the analysis of 3805 to 4505 sequences from 36 to 38 geographic localities depending on the gene segment data set. To assist in this we developed a maximum likelihood-based genetic algorithm to explore a wide range of complex spatial models, depicting a more complete picture of the migration network than determined previously.
conclusionsBased on phylogenies estimated from nucleotide sequence data sets, our results show that AIV migration rates are significantly higher within than between flyways, indicating that the migratory patterns of birds play a key role in viral dispersal. These findings provide valuable insights into the evolution, maintenance and transmission of AIVs, in turn allowing the development of improved programs for surveillance and risk assessment.
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