Evidence map›Paper›PMID 28545429›Full record

SynthesisBMC public health2017

Awareness, knowledge, perceptions, and attitudes towards genetic testing for cancer risk among ethnic minority groups: a systematic review.

Katie E J Hann, Madeleine Freeman, Lindsay Fraser, Jo Waller, Saskia C Sanderson, Belinda Rahman, Lucy Side, Sue Gessler, Anne Lanceley, PROMISE study team

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 6 pooled it
19.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 6 syntheses or guidelines pooled it, 312 citations in OpenAlex.

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132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Katie E J HannDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK.
Madeleine FreemanDepartment of Behavioural Science and Health, Institute of Epidemiology and Health Care, University College London, London, UK.
Lindsay FraserDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK.
Jo WallerDepartment of Behavioural Science and Health, Institute of Epidemiology and Health Care, University College London, London, UK.
Saskia C SandersonDepartment of Behavioural Science and Health, Institute of Epidemiology and Health Care, University College London, London, UK.
Belinda RahmanDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK.
Lucy SideDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK.
Sue GesslerDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK.
Anne LanceleyDepartment of Women's Cancer, EGA UCL Institute for Women's Health, University College London, London, UK. a.lanceley@ucl.ac.uk.
PROMISE study team
London Women's Clinic · GBInstitute for Reproductive Health · USUniversity College London · GB

Funding

Cancer Research UK 12677
6 · The paper itself

Abstract

backgroundGenetic testing for risk of hereditary cancer can help patients to make important decisions about prevention or early detection. US and UK studies show that people from ethnic minority groups are less likely to receive genetic testing. It is important to understand various groups' awareness of genetic testing and its acceptability to avoid further disparities in health care. This review aims to identify and detail awareness, knowledge, perceptions, and attitudes towards genetic counselling/testing for cancer risk prediction in ethnic minority groups.

methodsA search was carried out in PsycInfo, CINAHL, Embase and MEDLINE. Search terms referred to ethnicity, genetic testing/counselling, cancer, awareness, knowledge, attitudes, and perceptions. Quantitative and qualitative studies, written in English, and published between 2000 and 2015, were included.

resultsForty-one studies were selected for review: 39 from the US, and two from Australia. Results revealed low awareness and knowledge of genetic counselling/testing for cancer susceptibility amongst ethnic minority groups including African Americans, Asian Americans, and Hispanics. Attitudes towards genetic testing were generally positive; perceived benefits included positive implications for personal health and being able to inform family. However, negative attitudes were also evident, particularly the anticipated emotional impact of test results, and concerns about confidentiality, stigma, and discrimination. Chinese Australian groups were less studied, but of interest was a finding from qualitative research indicating that different views of who close family members are could impact on reported family history of cancer, which could in turn impact a risk assessment.

conclusionInterventions are needed to increase awareness and knowledge of genetic testing for cancer risk and to reduce the perceived stigma and taboo surrounding the topic of cancer in ethnic minority groups. More detailed research is needed in countries other than the US and across a broader spectrum of ethnic minority groups to develop effective culturally sensitive approaches for cancer prevention.

Indexed as

Genetic TestingAustraliaEthnicityHealth Knowledge, Attitudes, PracticeHumansMinority GroupsNeoplasmsRiskUnited StatesAttitudesAwarenessCancer riskEthnic minoritiesGenetic testingKnowledge

Identifiers

PMID28545429
PMCPMC5445407
OpenAlexW2619042849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.