ReviewBMC neurology2017
Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) in adults-a case report and literature review.
Review in BMC neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Adult-onset of mild encephalitis/encephalopathy with reversible splenial lesion (MERS): case report and systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Pooled it
- Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS): A case report and review of the literature.Radiology case reports · 2026Article
- Clinical, neuropsychological and radiological features in influenza virus-associated encephalitis: a case series.BMC neurology · 2026Article
- Clinical Advances in Child Neurology.Journal of clinical medicine · 2026Article
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- Transient Splenial Lesion Associated WithJournal of the American College of Emergency Physicians open · 2026Review
- A case of recurrent RESLES type I: analysis of pathogenic factors and delayed imaging manifestations.Frontiers in medicine · 2026Article
- Influenza B-Associated Mild Encephalopathy with Reversible Splenial Lesion in an Adult: A Case Report.Neurology international · 2025Article
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- Article
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- Meningitis Retention Syndrome With Mild Encephalopathy With a Reversible Splenial Lesion in a 30-Year-Old Woman: A Case Report.Case reports in radiology · 2025Article
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- Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS).PCN reports : psychiatry and clinical neurosciences · 2024Article
- Case report: Reversible splenial lesion syndrome preceding the onset of multiple sclerosis.Frontiers in immunology · 2024Article
- A case of mild encephalitis associated with COVID-19.Journal of general and family medicine · 2023Article
- Concurrent bacterial liver abscess and mild encephalitis/encephalopathy with reversible splenial lesion in a patient with poorly controlled type 2 diabetes.Diabetology international · 2023Article
- An elderly man with mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) without neuropsychiatric sequelae.Clinical case reports · 2023Article
- Japanese Spotted Fever Associated with Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion.Internal medicine (Tokyo, Japan) · 2023Article
- Case report: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion: an autopsy case.Frontiers in neurology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMild encephalitis/encephalopathy with reversible splenial lesion (MERS) is a rare clinico-radiological entity characterized by the magnetic resonance imaging (MRI) finding of a reversible lesion in the corpus callosum, sometimes involved the symmetrical white matters. Many cases of child-onset MERS with various causes have been reported. However, adult-onset MERS is relatively rare. The clinical characteristics and pathophysiologiccal mechanisms of adult-onset MERS are not well understood. We reviewed the literature on adult-onset MERS in order to describe the characteristics of MERS in adults and to provide experiences for clinician.
methodsWe reported a case of adult-onset MERS with acute urinary retension and performed literature search from PubMed and web of science databases to identify other adult-onset MERS reports from Januarary 2004 to March 2016. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed on selection process. And then we summarized the clinico-radiological features of adult-onset MERS.
resultsTwenty-nine adult-onset MERS cases were reviewed from available literature including the case we have. 86.2% of the cases (25/29) were reported in Asia, especially in Japan. Ages varied between 18 and 59 years old with a 12:17 female-to-male ratio. The major cause was infection by virus or bacteria. Fever and headache were the most common clinical manifestation, and acute urinary retention was observed in 6 patients. All patients recovered completely within a month.
conclusionAdult-onset MERS is an entity with a broad clinico-radiological spectrum because of the various diseases and conditions. There are similar characteristics between MERS in adults and children, also some differences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.