Evidence map›Paper›PMID 28545257›Full record

ReviewAntioxidants (Basel, Switzerland)2017

The Reactive Sulfur Species Concept: 15 Years On.

Gregory I Giles, Muhammad Jawad Nasim, Wesam Ali, Claus Jacob

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Comparison of Reactive Sites in 2(1Molecules (Basel, Switzerland) · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. A Whiff of Sulfur: One Wind a Day Keeps the Doctor Away.Antioxidants (Basel, Switzerland) · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gregory I GilesDepartment of Pharmacology and Toxicology, University of Otago, PO Box 56, Dunedin 9054, New Zealand. gregory.giles@otago.ac.nz.
Muhammad Jawad NasimDivision of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B2 1, Saarbruecken D-66123, Germany. jawad.nasim@uni-saarland.de.
Wesam AliDivision of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B2 1, Saarbruecken D-66123, Germany. s8wealii@stud.uni-saarland.de.
Claus JacobDivision of Bioorganic Chemistry, School of Pharmacy, Saarland University, Campus B2 1, Saarbruecken D-66123, Germany. c.jacob@mx.uni-saarland.de.
Saarland University · DEUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fifteen years ago, in 2001, the concept of "Reactive Sulfur Species" or RSS was advocated as a working hypothesis. Since then various organic as well as inorganic RSS have attracted considerable interest and stimulated many new and often unexpected avenues in research and product development. During this time, it has become apparent that molecules with sulfur-containing functional groups are not just the passive "victims" of oxidative stress or simple conveyors of signals in cells, but can also be stressors in their own right, with pivotal roles in cellular function and homeostasis. Many "exotic" sulfur-based compounds, often of natural origin, have entered the fray in the context of nutrition, ageing, chemoprevention and therapy. In parallel, the field of inorganic RSS has come to the forefront of research, with short-lived yet metabolically important intermediates, such as various sulfur-nitrogen species and polysulfides (S

Indexed as

cellular thiolstatreactive sulfur speciesredoxome.redox signallingsulfur radicals

Identifiers

PMID28545257
PMCPMC5488018
OpenAlexW2618256032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.