ArticleOncotarget2017
Characterization of Sudan Ebolavirus infection in ferrets.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Revisiting Ravn virus as the lesser known orthomarburgvirus.Npj viruses · 2026Review
- Rodent adapted marburg viruses are lethal in ferrets.Npj viruses · 2025Article
- Evaluation of Vaccines and Therapeutics Against Ebolaviruses in the Domestic Ferret.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Article
- Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control.Signal transduction and targeted therapy · 2024Review
- Review
- Natural history ofEmerging microbes & infections · 2022Article
- Development of a Well-Characterized Cynomolgus Macaque Model of Sudan Virus Disease for Support of Product Development.Vaccines · 2022Article
- Article
- Article
- Mucosal Challenge Ferret Models of Ebola Virus Disease.Pathogens (Basel, Switzerland) · 2021Article
- Pathogen Dose in Animal Models of Hemorrhagic Fever Virus Infections and the Potential Impact on Studies of the Immune Response.Pathogens (Basel, Switzerland) · 2021Review
- Taï Forest Virus Does Not Cause Lethal Disease in Ferrets.Microorganisms · 2021Article
- Lessons learned from Zaire ebolavirus to help address urgent needs for vaccines against Sudan ebolavirus and Marburg virus.Human vaccines & immunotherapeutics · 2020Article
- Article
- Virus inoculation and treatment regimens for evaluating anti-filovirus monoclonal antibody efficacyBiosafety and health · 2019Review
- Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir.Viruses · 2019Article
- Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans.The Journal of infectious diseases · 2018Article
- Marburg and Ravn Virus Infections Do Not Cause Observable Disease in Ferrets.The Journal of infectious diseases · 2018Article
- Modeling Ebola Virus Transmission Using Ferrets.mSphere · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Sudan virus (SUDV) outbreaks in Africa are highly lethal; however, the development and testing of novel antivirals and vaccines for this virus has been limited by a lack of suitable animal models. Non-human primates (NHP) remain the gold standard for modeling filovirus disease, but they are not conducive to screening large numbers of experimental compounds and should only be used to test the most promising candidates. Therefore, other smaller animal models are a valuable asset. We have recently developed a guinea-pig adapted SUDV virus that is lethal in guinea pigs. In our current study, we show that ferrets are susceptible to wild-type SUDV, providing a small animal model to directly study clinical isolates, screen experimental anti-SUDV compounds and potentially study viral transmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.