Evidence map›Paper›PMID 28544728›Full record

ArticleTropical medicine & international health : TM & IH2017

Index case finding facilitates identification and linkage to care of children and young persons living with HIV/AIDS in Malawi.

Saeed Ahmed, Rachael A Sabelli, Katie Simon, Nora E Rosenberg, Elijah Kavuta, Mwelura Harawa, Spencer Dick, Frank Linzie, Peter N Kazembe, Maria H Kim

Abstract readEvaluation Study
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Trial
  2. Financial Incentives for Pediatric HIV Testing in Kenya.The Pediatric infectious disease journal · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Saeed AhmedAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Rachael A SabelliAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Katie SimonAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Nora E RosenbergUniversity of North Carolina, Chapel Hill, NC, USA.
Elijah KavutaAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Mwelura HarawaAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Spencer DickAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Frank LinzieMalawi Ministry of Health, Lilongwe, Malawi.
Peter N KazembeAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.
Maria H KimAbbott Fund Children's Clinical Center of Excellence, Baylor College of Medicine, Lilongwe, Malawi.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Developing and Assessing a Male Engagement Intervention for Option B+ in MalawiR00MH104154 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROSENBERG, NORA · 2017 to 2019
$746k
Improving prevention of mother-to-child HIV transmission outcomes in MalawiK01TW009644 · FIC · BAYLOR COLLEGE OF MEDICINE · PI KIM, MARIA HYOUN · 2013 to 2017
$663k
FIC NIH HHS K01 TW009644NIAID NIH HHS P30 AI050410NIMH NIH HHS R00 MH104154
6 · The paper itself

Abstract

objectivesEvaluation of a novel index case finding and linkage-to-care programme to identify and link HIV-infected children (1-15 years) and young persons (>15-24 years) to care.

methodsHIV-infected patients enrolled in HIV services were screened and those who reported untested household members (index cases) were offered home- or facility-based HIV testing and counselling (HTC) of their household by a community health worker (CHW). HIV-infected household members identified were enrolled in a follow-up programme offering home and facility-based follow-up by CHWs.

resultsOf the 1567 patients enrolled in HIV services, 1030 (65.7%) were screened and 461 (44.8%) identified as index cases; 93.5% consented to HIV testing of their households and of those, 279 (64.7%) reported an untested child or young person. CHWs tested 711 children and young persons, newly diagnosed 28 HIV-infected persons (yield 4.0%; 95% CI: 2.7-5.6), and identified an additional two HIV-infected persons not enrolled in care. Of the 30 HIV-infected persons identified, 23 (76.6%) were linked to HIV services; 18 of the 20 eligible for ART (90.0%) were initiated. Median time (IQR) from identification to enrolment into HIV services was 4 days (1-8) and from identification to ART start was 6 days (1-8).

conclusionsAlmost half of HIV-infected patients enrolled in treatment services had untested household members, many of whom were children and young persons. Index case finding, coupled with home-based testing and tracked follow-up, is acceptable, feasible and facilitates the identification and timely linkage to care of HIV-infected children and young persons.

Indexed as

Community Health ServicesFamily CharacteristicsMass ScreeningAdolescentAdultAnti-HIV AgentsChildChild, PreschoolCommunity Health WorkersCounselingHIV InfectionsHumansMalawiYoung AdultAnti-HIV Agentsadolescentesadolescentscase findingdépistage du VIHhallazgo de casosHIV testingliaison aux soinslinkage to carepaediatric HIVprueba del VIHrecherche des casVIH pediátricoVIH pédiatriquevinculación a la atención

Identifiers

PMID28544728
PMCPMC5575466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.