ArticleInternational forum of allergy & rhinology2017
Computational fluid dynamics evaluation of posterior septectomy as a viable treatment option for large septal perforations.
Article in International forum of allergy & rhinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Surgical repair of large nasal septal perforation: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Pooled it
- On the comparison between pre- and post-surgery nasal anatomies via computational fluid dynamics.Biomechanics and modeling in mechanobiology · 2024Article
- Impact of nasal septal perforation on the airflow and air-conditioning characteristics of the nasal cavity.Scientific reports · 2024Article
- Is nasal airflow disrupted after endoscopic skull base surgery? A short review.Neurosurgical review · 2022Review
- Evidence of Nasal Cooling and Sensory Impairments Driving Patient Symptoms With Septal Deviation.The Laryngoscope · 2022Article
- Inferior meatus augmentation procedure (IMAP) normalizes nasal airflow patterns in empty nose syndrome patients via computational fluid dynamics (CFD) modeling.International forum of allergy & rhinology · 2021Article
- Peak Sinus Pressures During Sneezing in Healthy Controls and Post-Skull Base Surgery Patients.The Laryngoscope · 2020Article
- Computational fluid dynamic analysis of aggressive turbinate reductions: is it a culprit of empty nose syndrome?International forum of allergy & rhinology · 2019Article
- Asymptomatic vs symptomatic septal perforations: a computational fluid dynamics examination.International forum of allergy & rhinology · 2019Article
- Impact of Middle Turbinectomy on Airflow to the Olfactory Cleft: A Computational Fluid Dynamics Study.American journal of rhinology & allergy · 2019Article
- Computational fluid dynamics after endoscopic endonasal skull base surgery-possible empty nose syndrome in the context of middle turbinate resection.International forum of allergy & rhinology · 2019Article
- A CFD approach to understand nasoseptal perforations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Quantification of tissue-engineered trachea performance with computational fluid dynamics.The Laryngoscope · 2018Article
- Modeling congenital nasal pyriform aperture stenosis using computational fluid dynamics.International journal of pediatric otorhinolaryngology · 2018Article
- Nasal Structural and Aerodynamic Features That May Benefit Normal Olfactory Sensitivity.Chemical senses · 2018Article
- Investigation of the abnormal nasal aerodynamics and trigeminal functions among empty nose syndrome patients.International forum of allergy & rhinology · 2018Article
- Computational modeling and validation of human nasal airflow under various breathing conditions.Journal of biomechanics · 2017Article
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9 authors.
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Abstract
backgroundNumerous surgical techniques exist to treat nasal septal perforation (NSP). The surgical closure of large NSPs (>2 cm) is still challenging. Posterior septectomy has been reported as a simple alternative to treat large NSP, yet its mechanisms for symptom relief are not clear, and if failed, its consequence cannot be easily reversed.
methodsTen NSP patients were recruited: 5 underwent posterior septectomy and 5 underwent conventional flap or button repair. Computational fluid dynamics (CFD) simulated the nasal aerodynamics based on computed tomography (CT) scans. All patients had preoperative CT; however, only 4 had postoperative CT: 2 underwent posterior septectomy and the other 2 underwent flap repair. We examined surgical outcomes and the nasal airflow features among the 2 treatment options.
resultsBoth groups of patients had good outcomes based on chart review. Patients undergoing septectomy had significantly larger perforation size (2.32 ± 0.87 vs 1.21 ± 0.60 cm), higher flow rate across the perforation (47.8 ± 28.6 vs 18.3 ± 12.2 mL/second), and higher wall shear stress (WSS) along the posterior perforation margin (1.39 ± 0.52 vs 1.15 ± 0.58 Pa). The posterior WSS significantly correlated with crossover flow velocity (r = 0.77, p = 0.009) and was reduced by almost 67% postseptectomy, and by 29% postrepair.
conclusionThis is the first CFD analysis on an NSP patient cohort. NSP resulted in flow disturbance and increased WSS that potentially led to symptomatology. The removal of high stress points along the posterior margin may explain why posterior septectomy can be an effective treatment option. Aerodynamic abnormalities, in addition to perforation size and location, could serve as basis for future treatment decisions.
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