Evidence map›Paper›PMID 28544088›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Antivitamin B

Markus Ruetz, Aranganathan Shanmuganathan, Carmen Gherasim, Agnes Karasik, Robert Salchner, Christoph Kieninger, Klaus Wurst, Ruma Banerjee, Markos Koutmos, Bernhard Kräutler

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. An unusual Co-S bond links BProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Review
  5. Novel Method for the Synthesis of Hydroxycobalamin[International journal of molecular sciences · 2025
    Article
  6. The cobalamin processing enzyme of Trichoplax adhaerens.The Journal of biological chemistry · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Redox-Linked Coordination Chemistry Directs Vitamin BAccounts of chemical research · 2021
    Article
  12. Antivitamins BChemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Review
  13. Article
  14. Replacement of the Cobalt Center of Vitamin BAngewandte Chemie (International ed. in English) · 2020
    Article
  15. An Interprotein Co-S Coordination Complex in the BJournal of the American Chemical Society · 2020
    Article
  16. Ultrafast Excited State Dynamics and Fluorescence from Vitamin BThe journal of physical chemistry. B · 2020
    Article
  17. The human BThe Journal of biological chemistry · 2020
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Markus RuetzInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, 6020, Innsbruck, Austria.
Aranganathan ShanmuganathanDepartment of Biochemistry, Uniformed Services University of the Health Sciences, Bethesda, USA.
Carmen GherasimUniversity of Michigan Medical School, Ann Arbor, USA.
Agnes KarasikDepartment of Biochemistry, Uniformed Services University of the Health Sciences, Bethesda, USA.
Robert SalchnerInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, 6020, Innsbruck, Austria.
Christoph KieningerInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, 6020, Innsbruck, Austria.
Klaus WurstInstitute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Austria.ORCID 0000-0002-8774-9051
Ruma BanerjeeUniversity of Michigan Medical School, Ann Arbor, USA.
Markos KoutmosDepartment of Biochemistry, Uniformed Services University of the Health Sciences, Bethesda, USA.ORCID 0000-0003-0933-6312
Bernhard KräutlerInstitute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, 6020, Innsbruck, Austria.ORCID 0000-0002-2222-0587
Universität Innsbruck · ATUniformed Services University of the Health Sciences · USUniversity of Michigan · USUniversity of Utah · US

Funding

REACTION MECHANISMS OF MAMMALIAN B12-DEPENDENT ENZYMESR01DK045776 · NIDDK · UNIVERSITY OF NEBRASKA LINCOLN · PI RUMA V BANERJEE · 1998 to 2026
$9.7M
Austrian Science Fund FWF P 28892NIDDK NIH HHS R01 DK045776
6 · The paper itself

Abstract

B

Indexed as

Catalytic DomainCrystallography, X-RayFluorineGlutathioneHumansHydrolysisKineticsModels, MolecularMolecular StructureSpectrum AnalysisSubstrate SpecificityTemperatureVitamin B 12F2PhEtyCblFluorineGlutathioneVitamin B 12antivitaminsenzyme inhibitorsglutathioneprotein crystallographyvitamin B12

Identifiers

PMID28544088
PMCPMC5681751
OpenAlexW2617502799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.