Evidence map›Paper›PMID 28544041›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2017

Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals.

Varpu Elenius, Eija Bergroth, Petri Koponen, Sami Remes, Pedro A Piedra, Janice A Espinola, Matti Korppi, Carlos A Camargo, Tuomas Jartti

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. βNature communications · 2025
    Article
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  6. The use of βERJ open research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Varpu EleniusDepartment of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland.
Eija BergrothDepartment of Paediatrics, Kuopio University Hospital, Kuopio, Finland.
Petri KoponenDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.
Sami RemesDepartment of Paediatrics, Kuopio University Hospital, Kuopio, Finland.
Pedro A PiedraDepartments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Janice A EspinolaDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Matti KorppiDepartment of Paediatrics, Tampere University Hospital, Tampere, Finland.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Tuomas JarttiDepartment of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimInfants hospitalised for bronchiolitis undergo examinations and treatments not supported by current research evidence and we investigated practice variations with regard to Finnish children under the age of two.

methodsThis prospective, multicentre cohort study was conducted in paediatric units in three university hospitals in Finland from 2008 to 2010. Hospital medical records were reviewed to collect data on clinical course, testing and treatment. Data were analysed separately for children meeting our strict definition of bronchiolitis, aged under 12 months without a history of wheezing, and a loose definition, aged 12-23 months or with a history of wheezing.

resultsThe median age of the 408 children was 8.1 months. Clinical management varied between the three hospitals when stratified by strict and loose bronchiolitis subgroup definitions: complete blood counts ranged from 15-95% vs 16-94%, respectively, and the other measures were chest x-ray (16-91% vs 14-72%), intravenous fluids (2-47% vs 2-41%), use of nebulised epinephrine (10-84% vs 7-50%), use of salbutamol (18-21% vs 13-84%) and use of corticosteroids (6-23% vs 60-76%).

conclusionThe clinical management of bronchiolitis varied considerably with regard to the three hospitals and the two definitions of bronchiolitis. A stronger commitment to evidence-based bronchiolitis guidelines is needed in Finland.

Indexed as

Administration, InhalationAlbuterolBronchiolitisBronchodilator AgentsCohort StudiesEpinephrineFemaleFinlandHumansInfantInfant, NewbornMaleAlbuterolBronchodilator AgentsEpinephrineBronchiolitis guidelinesBronchiolitis treatmentHistory of wheezingHospitalised infantsPractice variations

Identifiers

PMID28544041
PMCPMC7159377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.